Reactome | Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)

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Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100885
displayName	Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
eventOf	[Pathway:R-MMU-2142753] Arachidonate metabolism - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2162255] omega-hydroxylase P450 pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-2161795] Arachidonate is hydroxylated to 16-HETE by CYP(1) - Mus musculus [Reaction:R-MMU-9915992] Arachidonate is hydroxylated to 17-HETE by CYP(1) - Mus musculus [Reaction:R-MMU-9915993] Arachidonate is hydroxylated to 18-HETE by CYP(1) - Mus musculus [Reaction:R-MMU-2161814] Arachidonate is hydroxylated to 19-HETE by CYP(2) - Mus musculus [Reaction:R-MMU-2161940] Arachidonate is hydroxylated to 20-HETE by CYP(3) - Mus musculus
inferredFrom	[Pathway:R-HSA-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-2142816
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-2142753] Arachidonate metabolism
(inferredTo)	[Pathway:R-HSA-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)

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