Reactome | HP1 alpha binds Histone H3K9(me)3

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HP1 alpha binds Histone H3K9(me)3 Show undefined attributes

authored	[InstanceEdit:983205] Akkerman, JW, 2010-10-29
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:994099] Jupe, S, 2010-11-05
dbId	994106
displayName	HP1 alpha binds Histone H3K9(me)3
edited	[InstanceEdit:1013888] Jupe, S, 2010-11-12
eventOf	[Pathway:R-HSA-983231] Factors involved in megakaryocyte development and platelet production - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-994093] CBX5 [nucleoplasm] [DefinedSet:R-HSA-427391] Histone H3 methylated at lysine-9 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:212040] Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins [URL:994105] http://www.thesgc.org/structures/structure_description/3FDT/
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	HP1 alpha binds Histone H3K9(me)3
orthologousEvent	[Reaction:R-PFA-994106] HP1 alpha binds Histone H3K9(me)3 - Plasmodium falciparum [Reaction:R-CEL-994106] HP1 alpha binds Histone H3K9(me)3 - Caenorhabditis elegans [Reaction:R-DME-994106] HP1 alpha binds Histone H3K9(me)3 - Drosophila melanogaster [Reaction:R-GGA-994106] HP1 alpha binds Histone H3K9(me)3 - Gallus gallus [Reaction:R-DRE-994106] HP1 alpha binds Histone H3K9(me)3 - Danio rerio [Reaction:R-SSC-994106] HP1 alpha binds Histone H3K9(me)3 - Sus scrofa [Reaction:R-BTA-994106] HP1 alpha binds Histone H3K9(me)3 - Bos taurus [Reaction:R-CFA-994106] HP1 alpha binds Histone H3K9(me)3 - Canis familiaris [Reaction:R-RNO-994106] HP1 alpha binds Histone H3K9(me)3 - Rattus norvegicus [Reaction:R-MMU-994106] HP1 alpha binds Histone H3K9(me)3 - Mus musculus
output	[Complex:R-HSA-994100] HP1alpha:Histone H3 methylated at K9 [nucleoplasm]
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1013883] Ouwehand, WH, 2010-11-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-994106
summation	[Summation:994101] Chromobox (CBX) genes encode members of the Heterochromatin ...

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[Pathway:R-HSA-983231] Factors involved in megakaryocyte development and platelet production