Reactome | CBX5 [nucleoplasm]

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CBX5 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9843929] CBX5:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-4615933] SUMOylation of CBX5 with SUMO1 - Homo sapiens [Reaction:R-HSA-994106] HP1 alpha binds Histone H3K9(me)3 - Homo sapiens [Reaction:R-HSA-9843978] CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin - Homo sapiens
created	[InstanceEdit:994099] Jupe, S, 2010-11-05
dbId	994093
displayName	CBX5 [nucleoplasm]
endCoordinate	191
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-4616022] Cbx5 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-994093] Cbx5 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-994093] CBX5 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-994093] CBX5 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-994093] CBX5 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-994093] cbx5 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-GGA-994093] CBX5 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-994093] Su(var)205 [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-994093-2] rhi [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-994093-3] Chro [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-994093-4] HP1c [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-994093-5] HP1e [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-994093-6] CC4 [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-994093-7] HP1b [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-994093-8] Homologues of CBX5 [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-994093] hpl-1 [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-994093-2] cec-1 [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-994093-3] cec-3 [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-994093-4] cec-6 [nucleoplasm] - Caenorhabditis elegans [DefinedSet:R-CEL-994093-5] Homologues of CBX5 [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-994093] hcpA [nucleoplasm] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-994093-2] hcpB [nucleoplasm] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-DDI-994093-3] hcpC [nucleoplasm] - Dictyostelium discoideum [DefinedSet:R-DDI-994093-4] Homologues of CBX5 [nucleoplasm] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-994093] chp2 [nucleoplasm] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SPO-994093-2] swi6 [nucleoplasm] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SPO-994093-3] chp1 [nucleoplasm] - Schizosaccharomyces pombe [DefinedSet:R-SPO-994093-4] Homologues of CBX5 [nucleoplasm] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-PFA-994093] CBX5 [nucleoplasm] - Plasmodium falciparum
maxDepth	1
modified	[InstanceEdit:3632907] Wu, G, 2013-05-28
name	CBX5 Heterochromatin protein 1 homolog alpha Chromobox protein homolog 5 CBX5_HUMAN
producedByEvent	[BlackBoxEvent:R-HSA-9007646] CBX5 gene expression is inhibited by E2F6 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P45973] UniProt:P45973 CBX5
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-994093
startCoordinate	1

Referrals

(input)	[Reaction:R-HSA-4615933] SUMOylation of CBX5 with SUMO1 [Reaction:R-HSA-9843978] CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [Reaction:R-HSA-994106] HP1 alpha binds Histone H3K9(me)3
(hasComponent)	[Complex:R-HSA-9843929] CBX5:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement [nucleoplasm] [Complex:R-HSA-994100] HP1alpha:Histone H3 methylated at K9 [nucleoplasm]
(output)	[BlackBoxEvent:R-HSA-9007646] CBX5 gene expression is inhibited by E2F6

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