Reactome | Factors involved in megakaryocyte development and platelet production

Schema > Pathway > Entries

Factors involved in megakaryocyte development and platelet production Show undefined attributes

authored	[InstanceEdit:983205] Akkerman, JW, 2010-10-29
created	[InstanceEdit:983242] Jupe, S, 2010-10-29
dbId	983231
displayName	Factors involved in megakaryocyte development and platelet production
edited	[InstanceEdit:1013888] Jupe, S, 2010-11-12
eventOf	[TopLevelPathway:R-HSA-109582] Hemostasis - Homo sapiens
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-HSA-983285] RAD51B binds RAD51C - Homo sapiens [Reaction:R-HSA-983218] RAD51B:RAD51C binds single-stranded DNA - Homo sapiens [Reaction:R-HSA-992708] Dual-specific AKAPs bind type I and II PKA regulatory subunits - Homo sapiens [Reaction:R-HSA-992703] Mitofusins trans-interact linking mitochondria prior to fusion - Homo sapiens [Reaction:R-HSA-992696] p53, SIN3A and MYB form a complex - Homo sapiens [Reaction:R-HSA-994020] IRF1 binds the promoters of Interferon alpha and beta - Homo sapiens [BlackBoxEvent:R-HSA-994034] Expression of Interferon-alpha and beta - Homo sapiens [Reaction:R-HSA-994038] IRF2 binds the promoters of Interferon alpha and beta - Homo sapiens [Reaction:R-HSA-994106] HP1 alpha binds Histone H3K9(me)3 - Homo sapiens [Reaction:R-HSA-994137] ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 - Homo sapiens [Reaction:R-HSA-994140] ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 - Homo sapiens [Reaction:R-HSA-2267372] ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 - Homo sapiens [Reaction:R-HSA-994148] LRRC16A binds F-actin capping protein - Homo sapiens [Reaction:R-HSA-879459] F-actin capping protein is a heterodimer - Homo sapiens [Reaction:R-HSA-994169] F-actin capping protein binds to the barbed end of elongating F-actin - Homo sapiens [BlackBoxEvent:R-HSA-8865107] MICAL1 produces NADP+, H2O2 - Homo sapiens [Reaction:R-HSA-996727] REST recruits the BHC complex - Homo sapiens [Reaction:R-HSA-996755] ZFPM proteins bind GATA proteins - Homo sapiens [Reaction:R-HSA-997263] JMJD1C demethylates H3K9 mono- and di-methylation - Homo sapiens [Reaction:R-HSA-997237] SH2B proteins bind JAK2 - Homo sapiens [Reaction:R-HSA-1008248] Adenylate Kinase 3 is a GTP-AMP phosphotransferase - Homo sapiens [Reaction:R-HSA-1008240] NFE2 is a heterodimer - Homo sapiens [Reaction:R-HSA-1008200] NFE2 binds the beta globin locus control region - Homo sapiens [BlackBoxEvent:R-HSA-1008220] Expression of globin genes under control of the beta globin control region - Homo sapiens [Reaction:R-HSA-1011576] EHD proteins interact with Rabenosyn-5 - Homo sapiens [Reaction:R-HSA-1011600] Rabenosyn-5 connects Rab5 to VPS-45 - Homo sapiens [Reaction:R-HSA-1011598] DOCKs bind to RhoGEFs - Homo sapiens [Reaction:R-HSA-1013833] Cables link CDK5 and ABL1 - Homo sapiens [Reaction:R-HSA-1013881] Cables1 links CDK2 and WEE1 - Homo sapiens [Pathway:R-HSA-983189] Kinesins - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1013931] Megakaryocyte development and platelet production [LiteratureReference:1013930] Transcriptional control of megakaryocyte development [LiteratureReference:1027318] From hematopoietic stem cells to platelets
modified	[InstanceEdit:10931649] Wright, Adam, 2024-03-08
name	Factors involved in megakaryocyte development and platelet production
orthologousEvent	[Pathway:R-MMU-983231] Factors involved in megakaryocyte development and platelet production - Mus musculus [Pathway:R-RNO-983231] Factors involved in megakaryocyte development and platelet production - Rattus norvegicus [Pathway:R-CFA-983231] Factors involved in megakaryocyte development and platelet production - Canis familiaris [Pathway:R-BTA-983231] Factors involved in megakaryocyte development and platelet production - Bos taurus [Pathway:R-SSC-983231] Factors involved in megakaryocyte development and platelet production - Sus scrofa [Pathway:R-DRE-983231] Factors involved in megakaryocyte development and platelet production - Danio rerio [Pathway:R-XTR-983231] Factors involved in megakaryocyte development and platelet production - Xenopus tropicalis [Pathway:R-GGA-983231] Factors involved in megakaryocyte development and platelet production - Gallus gallus [Pathway:R-DME-983231] Factors involved in megakaryocyte development and platelet production - Drosophila melanogaster [Pathway:R-CEL-983231] Factors involved in megakaryocyte development and platelet production - Caenorhabditis elegans [Pathway:R-DDI-983231] Factors involved in megakaryocyte development and platelet production - Dictyostelium discoideum [Pathway:R-SPO-983231] Factors involved in megakaryocyte development and platelet production - Schizosaccharomyces pombe [Pathway:R-SCE-983231] Factors involved in megakaryocyte development and platelet production - Saccharomyces cerevisiae [Pathway:R-PFA-983231] Factors involved in megakaryocyte development and platelet production - Plasmodium falciparum
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1013883] Ouwehand, WH, 2010-11-12
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-983231
summation	[Summation:1013916] Megakaryocytes (MKs) give rise to circulating platelets (thr...

Referrals

(hasEvent)

[TopLevelPathway:R-HSA-109582] Hemostasis

Cite Us!