Reactome | CBX5 gene expression is inhibited by E2F6

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CBX5 gene expression is inhibited by E2F6 Show undefined attributes

authored	[InstanceEdit:9007684] Orlic-Milacic, Marija, 2017-05-31
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9007649] Orlic-Milacic, Marija, 2017-05-31
dbId	9007646
displayName	CBX5 gene expression is inhibited by E2F6
edited	[InstanceEdit:9007684] Orlic-Milacic, Marija, 2017-05-31
eventOf	[Pathway:R-HSA-8953750] Transcriptional Regulation by E2F6 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9007651] CBX5 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9007077] E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CBX5 gene expression is inhibited by E2F6
output	[EntityWithAccessionedSequence:R-HSA-994093] CBX5 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9007647] E2F6 binds CBX5 gene promoter - Homo sapiens
regulatedBy	[NegativeGeneExpressionRegulation:R-HSA-9007650] Negative gene expression regulation by 'E2F6:(TFDP1,TFDP2):CBX5 gene [nucleoplasm]'
regulationReference	[RegulationReference:9642627] Negative gene expression regulation by 'E2F6:(TFDP1,TFDP2):CBX5 gene [nucleoplasm]' E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9005633] Herlihy, Anna, 2017-05-12
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9007646
summation	[Summation:9007648] Transcription of the CBX5 (HP1alpha) gene is inhibited by bi...

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[Pathway:R-HSA-8953750] Transcriptional Regulation by E2F6

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