Reactome | Formation of ChAHP complex

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Formation of ChAHP complex Show undefined attributes

authored	[InstanceEdit:9937860] Rothfels, Karen, 2025-02-07
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9940461] Rothfels, Karen, 2025-03-05
dbId	9940477
displayName	Formation of ChAHP complex
edited	[InstanceEdit:9937860] Rothfels, Karen, 2025-02-07
eventOf	[Pathway:R-HSA-9940465] ChAHP complex assembly - Homo sapiens
followingEvent	[Reaction:R-HSA-9940460] ChAHP binds SINE elements - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9940393] ADNP [nucleoplasm] [DefinedSet:R-HSA-9940425] CBX1,CBX3 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-3702078] CHD4 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9940346] Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes [LiteratureReference:9938067] The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse [LiteratureReference:9940356] A SWI/SNF-related autism syndrome caused by de novo mutations in ADNP [LiteratureReference:9940177] The chromatin remodeler ADNP regulates neurodevelopmental disorder risk genes and neocortical neurogenesis
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Formation of ChAHP complex
orthologousEvent	[Reaction:R-GGA-9940477] Formation of ChAHP complex - Gallus gallus [Reaction:R-DRE-9940477] Formation of ChAHP complex - Danio rerio [Reaction:R-SSC-9940477] Formation of ChAHP complex - Sus scrofa [Reaction:R-BTA-9940477] Formation of ChAHP complex - Bos taurus [Reaction:R-CFA-9940477] Formation of ChAHP complex - Canis familiaris [Reaction:R-RNO-9940477] Formation of ChAHP complex - Rattus norvegicus [Reaction:R-MMU-9940477] Formation of ChAHP complex - Mus musculus
output	[Complex:R-HSA-9940447] ChAHP complex [nucleoplasm]
releaseDate	2026-03-25
releaseStatus	NEW
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9940477
summation	[Summation:9940469] ChAHP is a CHD4-containing complex that plays a role in larg...

Referrals

(precedingEvent)	[Reaction:R-HSA-9940460] ChAHP binds SINE elements
(hasEvent)	[Pathway:R-HSA-9940465] ChAHP complex assembly