Reactome | ChAHP complex assembly

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ChAHP complex assembly Show undefined attributes

authored	[InstanceEdit:9937860] Rothfels, Karen, 2025-02-07
created	[InstanceEdit:9940461] Rothfels, Karen, 2025-03-05
dbId	9940465
displayName	ChAHP complex assembly
edited	[InstanceEdit:9937860] Rothfels, Karen, 2025-02-07
eventOf	[Pathway:R-HSA-9943965] CHD3, CHD4, CHD5 subfamily - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-9940477] Formation of ChAHP complex - Homo sapiens [Reaction:R-HSA-9940466] Formation of ChAHP2 complex - Homo sapiens [Reaction:R-HSA-9940473] ChAHP2 binds H3K9me3 at LTR and LINE elements - Homo sapiens [Reaction:R-HSA-9940460] ChAHP binds SINE elements - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9938062] Sentinels of chromatin: chromodomain helicase DNA-binding proteins in development and disease [LiteratureReference:9940346] Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes [LiteratureReference:9938067] The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse [LiteratureReference:9940308] ChAHP2 and ChAHP control diverse retrotransposons by complementary activities [LiteratureReference:9940362] Discovery of a DNA methylation profile in individuals with Sifrim-Hitz-Weiss syndrome [LiteratureReference:9940177] The chromatin remodeler ADNP regulates neurodevelopmental disorder risk genes and neocortical neurogenesis
maxDepth	2
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	ChAHP complex assembly
orthologousEvent	[Pathway:R-GGA-9940465] ChAHP complex assembly - Gallus gallus [Pathway:R-DRE-9940465] ChAHP complex assembly - Danio rerio [Pathway:R-SSC-9940465] ChAHP complex assembly - Sus scrofa [Pathway:R-BTA-9940465] ChAHP complex assembly - Bos taurus [Pathway:R-CFA-9940465] ChAHP complex assembly - Canis familiaris [Pathway:R-RNO-9940465] ChAHP complex assembly - Rattus norvegicus [Pathway:R-MMU-9940465] ChAHP complex assembly - Mus musculus
releaseDate	2026-03-25
releaseStatus	NEW
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9940465
summation	[Summation:9940456] In addition to acting monomerically or as part of various Nu...

Referrals

(hasEvent)

[Pathway:R-HSA-9943965] CHD3, CHD4, CHD5 subfamily