Reactome | Formation of neuronal progenitor BAF (npBAF)

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Formation of neuronal progenitor BAF (npBAF) Show undefined attributes

authored	[InstanceEdit:9934146] Rothfels, Karen, 2025-01-06
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9934025] Rothfels, Karen, 2025-01-06
dbId	9934021
displayName	Formation of neuronal progenitor BAF (npBAF)
edited	[InstanceEdit:9934146] Rothfels, Karen, 2025-01-06
eventOf	[Pathway:R-HSA-9934037] Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) - Homo sapiens
followingEvent	[Reaction:R-HSA-9934023] Formation of neural BAF (nBAF) - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-5225635] ARID1B [nucleoplasm] [Complex:R-HSA-9934006] esBAF [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-389256] SMARCA2 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9932762] An essential switch in subunit composition of a chromatin remodeling complex during neural development [LiteratureReference:9933255] Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways [LiteratureReference:9933264] Creating a neural specific chromatin landscape by npBAF and nBAF complexes [LiteratureReference:9933220] Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics [LiteratureReference:9933957] GBAF, a small BAF sub-complex with big implications: a systematic review [LiteratureReference:9933218] COMPASS and SWI/SNF complexes in development and disease
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Formation of neuronal progenitor BAF (npBAF)
orthologousEvent	[Reaction:R-CEL-9934021] Formation of neuronal progenitor BAF (npBAF) - Caenorhabditis elegans [Reaction:R-DME-9934021] Formation of neuronal progenitor BAF (npBAF) - Drosophila melanogaster [Reaction:R-GGA-9934021] Formation of neuronal progenitor BAF (npBAF) - Gallus gallus [Reaction:R-XTR-9934021] Formation of neuronal progenitor BAF (npBAF) - Xenopus tropicalis [Reaction:R-BTA-9934021] Formation of neuronal progenitor BAF (npBAF) - Bos taurus [Reaction:R-CFA-9934021] Formation of neuronal progenitor BAF (npBAF) - Canis familiaris [Reaction:R-RNO-9934021] Formation of neuronal progenitor BAF (npBAF) - Rattus norvegicus [Reaction:R-MMU-9934021] Formation of neuronal progenitor BAF (npBAF) - Mus musculus
output	[Complex:R-HSA-9934008] npBAF [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-5225626] SMARCD2 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9934024] SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 - Homo sapiens
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-03-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9938992] Dykhuizen, Emily C, 2025-02-21
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9934021
summation	[Summation:9933994] Studies in mice identified a neural progenitor (np) BAF comp...

Referrals

(precedingEvent)	[NegativePrecedingEvent:9934143] Futile Cycle: Formation of neuronal progenitor BAF (npBAF) [Reaction:R-HSA-9934023] Formation of neural BAF (nBAF) [NegativePrecedingEvent:9934139] Futile Cycle: Formation of neuronal progenitor BAF (npBAF)
(hasEvent)	[Pathway:R-HSA-9934037] Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)

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