Reactome | Formation of neural BAF (nBAF)

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Formation of neural BAF (nBAF) Show undefined attributes

authored	[InstanceEdit:9934146] Rothfels, Karen, 2025-01-06
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9934025] Rothfels, Karen, 2025-01-06
dbId	9934023
displayName	Formation of neural BAF (nBAF)
edited	[InstanceEdit:9934146] Rothfels, Karen, 2025-01-06
eventOf	[Pathway:R-HSA-9934037] Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) - Homo sapiens
inferredFrom	[Reaction:R-MMU-9934111] Formation of neural BAF (nBaf) - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-5225616] ACTL6B [nucleoplasm] [DefinedSet:R-HSA-9933977] DPF1, DPF3 [nucleoplasm] [Complex:R-HSA-9934008] npBAF [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9727481] SS18L1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:9934173] Identification of a polymorphic, neuron-specific chromatin remodeling complex [LiteratureReference:9932762] An essential switch in subunit composition of a chromatin remodeling complex during neural development [LiteratureReference:9933255] Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways [LiteratureReference:9933264] Creating a neural specific chromatin landscape by npBAF and nBAF complexes [LiteratureReference:9933220] Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics [LiteratureReference:9933957] GBAF, a small BAF sub-complex with big implications: a systematic review [LiteratureReference:9933218] COMPASS and SWI/SNF complexes in development and disease
maxDepth	1
modified	[InstanceEdit:9939454] Rothfels, Karen, 2025-02-27
name	Formation of neural BAF (nBAF)
output	[EntityWithAccessionedSequence:R-HSA-2980912] ACTL6A [nucleoplasm] [DefinedSet:R-HSA-9933980] DPF2,PHF10 [nucleoplasm] [Complex:R-HSA-9934005] nBAF [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9727441] SS18 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9934021] Formation of neuronal progenitor BAF (npBAF) - Homo sapiens
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-03-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9938992] Dykhuizen, Emily C, 2025-02-21
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9934023
summation	[Summation:9934135] Biochemical and affinity purification steps performed on mou...

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(precedingEvent)	[NegativePrecedingEvent:9934142] Futile Cycle: Formation of neural BAF (nBAF) [NegativePrecedingEvent:9934140] Futile Cycle: Formation of neural BAF (nBAF) [NegativePrecedingEvent:9934141] Futile Cycle: Formation of neural BAF (nBAF)
(hasEvent)	[Pathway:R-HSA-9934037] Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
(inferredTo)	[Reaction:R-MMU-9934111] Formation of neural BAF (nBaf)