Studies in mice identified a neural progenitor (np) BAF comp...

created [InstanceEdit:9933998] Rothfels, Karen, 2025-01-06
dbId 9933994
displayName Studies in mice identified a neural progenitor (np) BAF comp...
modified [InstanceEdit:9934292] Rothfels, Karen, 2025-01-07
schemaClass Summation
text Studies in mice identified a neural progenitor (np) BAF complex that is required for the proliferation of neural stem and progenitor cells (Lessard et al, 2007; Staahl et al, 2013). These complexes differ slightly from esBAF complexes in subunit composition. npBAF complexes contain either SMARCA4 or SMARCA2 as catalytic subunits, may contain either ARID1A or ARID1B, and contain SMARCD1 and SMARCD3 but not SMARCD2 (Lessard et al, 2007; Stahl et al, 2013; reviewed in Staahl and Crabtree, 2013; Kadoch and Crabtree, 2015; Cenik and Shilatifard, 2021; Innis and Cabot, 2020).
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