Reactome | C binds histones

Schema > Reaction > Entries

authored	[InstanceEdit:9921242] Stephan, Ralf, 2024-09-08
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9921298] Stephan, Ralf, 2024-09-09
crossReference	[DatabaseIdentifier:12020825] Mondo:0005502
dbId	9921290
disease	[Disease:3244610] dengue disease
displayName	C binds histones
edited	[InstanceEdit:9970471] Stephan, Ralf, 2025-10-30
eventOf	[Pathway:R-HSA-9918481] Dengue Virus-Host Interactions - Homo sapiens
input	[Complex:R-DVI-9922241] C dimer [nucleoplasm] [DefinedSet:R-HSA-9921300] DENV C histone ligands [nucleoplasm]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9921312] Dengue virus capsid protein binds core histones and inhibits nucleosome formation in human liver cells
maxDepth	1
modified	[InstanceEdit:9970472] Stephan, Ralf, 2025-10-30
name	C binds histones
output	[Complex:R-HSA-9921294] C:Histones [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-HSA-9919944] C dimer localizes to nucleus - Homo sapiens
previousReviewStatus	[ReviewStatus:9821383] three stars
relatedSpecies	[Species:3244621] Dengue virus type 2
releaseDate	2025-12-08
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9970439] Roque Ascen��o, Fernando, 2025-10-29 [InstanceEdit:9970204] Mansur, Daniel Santos, 2025-10-29
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9921290
summation	[Summation:9921280] Nuclear DENV C (capsid) protein binds histones H2A, H2B, H3,...

(hasEvent)

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