Reactome | factor XII [extracellular region]

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-HSA-9936901] factor XII:?-amyloid fibril:Zn2+ [extracellular region] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9936909] factor XII + ?-amyloid fibril:Zn2+ -> factor XII:?-amyloid fibril:Zn2+ - Homo sapiens [Reaction:R-HSA-9855705] factor XII + polyanionic activator -> factor XII:polyanionic activator (in plasma) - Homo sapiens [Reaction:R-HSA-9855685] factor XII + prekallikrein:kininogen:cell surface receptor -> prekallikrein:kininogen:cell surface receptor:factor XII - Homo sapiens
created	[InstanceEdit:9855678] Shamovsky, Veronica, 2023-12-07
dbId	9855700
displayName	factor XII [extracellular region]
endCoordinate	615
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-9855700] F12 [extracellular region] - Mus musculus [EntityWithAccessionedSequence:R-RNO-9855700] F12 [extracellular region] - Rattus norvegicus [GenomeEncodedEntity:R-CFA-9855700] Ghost homologue of factor XII [extracellular region] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-9855700] F12 [extracellular region] - Bos taurus [EntityWithAccessionedSequence:R-SSC-9855700] F12 [extracellular region] - Sus scrofa [GenomeEncodedEntity:R-DRE-9855700] Ghost homologue of factor XII [extracellular region] - Danio rerio [EntityWithAccessionedSequence:R-XTR-9855700] f12 [extracellular region] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-9855700] factor XII [extracellular region] - Gallus gallus
maxDepth	1
name	factor XII Hageman factor
referenceEntity	[ReferenceGeneProduct:uniprot:P00748] UniProt:P00748 F12
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9855700
startCoordinate	20

(hasComponent)	[Complex:R-HSA-9936901] factor XII:?-amyloid fibril:Zn2+ [extracellular region] [Complex:R-HSA-9909047] kallikrein:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] [Complex:R-HSA-9857879] FXII:polyanionic activator [extracellular region] [Complex:R-HSA-9857822] KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane]
(input)	[Reaction:R-HSA-9936909] factor XII + ?-amyloid fibril:Zn2+ -> factor XII:?-amyloid fibril:Zn2+ [Reaction:R-HSA-9855705] factor XII + polyanionic activator -> factor XII:polyanionic activator (in plasma) [Reaction:R-HSA-9855685] factor XII + prekallikrein:kininogen:cell surface receptor -> prekallikrein:kininogen:cell surface receptor:factor XII
(activeUnit)	[CatalystActivity:9904350] serine-type endopeptidase activity of FXII:polyanionic activator [extracellular region]

factor XII [extracellular region] Show undefined attributes

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