Reactome | KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane]

Schema > Complex > Entries

KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:9855680] serine-type endopeptidase activity of KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-9909048] prekallikrein:kininogen:cell surface receptor:factor XII -> kallikrein:kininogen:cell surface receptor:factor XII (FXII catalyst) - Homo sapiens [Reaction:R-HSA-9857814] prekallikrein:kininogen:cell surface receptor:factor XII -> factor XIIa + prekallikrein:kininogen:cell surface receptor (FXII autocatalysis on the cell surface) - Homo sapiens
created	[InstanceEdit:9857816] Shamovsky, Veronica, 2024-01-09
dbId	9857822
displayName	KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-9855700] factor XII [extracellular region] [Complex:R-HSA-9857960] KLKB1:KNG1:(C1QBP, C1QBP:KRT1, PLAUR:KRT1) [plasma membrane]
inDisease	false
includedLocation	[Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-9857822] KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] - Mus musculus [Complex:R-RNO-9857822] KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] - Rattus norvegicus [Complex:R-BTA-9857822] KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] - Bos taurus [Complex:R-SSC-9857822] KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] - Sus scrofa [Complex:R-XTR-9857822] KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-9857822] KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane] - Gallus gallus
isChimeric	false
maxDepth	6
modified	[InstanceEdit:9909026] Shamovsky, Veronica, 2024-04-25
name	KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII prekallikrein:kininogen:cell surface receptor:factor XII
producedByEvent	[Reaction:R-HSA-9855685] factor XII + prekallikrein:kininogen:cell surface receptor -> prekallikrein:kininogen:cell surface receptor:factor XII - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9857822

Referrals

(input)	[Reaction:R-HSA-9909048] prekallikrein:kininogen:cell surface receptor:factor XII -> kallikrein:kininogen:cell surface receptor:factor XII (FXII catalyst) [Reaction:R-HSA-9857814] prekallikrein:kininogen:cell surface receptor:factor XII -> factor XIIa + prekallikrein:kininogen:cell surface receptor (FXII autocatalysis on the cell surface)
(physicalEntity)	[CatalystActivity:9855680] serine-type endopeptidase activity of KLKB1:KNG1:(C1QBP,C1QBP:KRT1, PLAUR:KRT1):FXII [plasma membrane]
(output)	[Reaction:R-HSA-9855685] factor XII + prekallikrein:kininogen:cell surface receptor -> prekallikrein:kininogen:cell surface receptor:factor XII

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