Reactome | REXO2 hydrolyzes 4-5 nucleotide RNAs to ribonucleotides

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REXO2 hydrolyzes 4-5 nucleotide RNAs to ribonucleotides Show undefined attributes

authored	[InstanceEdit:9836824] May, Bruce, 2023-06-05
catalystActivity	[CatalystActivity:9836830] 3'-5'-RNA exonuclease activity of REXO2 tetramer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9836820] May, Bruce, 2023-06-05
dbId	9836822
displayName	REXO2 hydrolyzes 4-5 nucleotide RNAs to ribonucleotides
edited	[InstanceEdit:9836824] May, Bruce, 2023-06-05
eventOf	[Pathway:R-HSA-9836573] Mitochondrial RNA degradation - Homo sapiens
input	[GenomeEncodedEntity:R-HSA-9836823] 4-5 nt RNA [mitochondrial matrix] 4 × [SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9836831] REXO2 is an oligoribonuclease active in human mitochondria [LiteratureReference:9836838] Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA
maxDepth	1
modified	[InstanceEdit:9841153] May, Bruce, 2023-08-09
name	REXO2 hydrolyzes 4-5 nucleotide RNAs to ribonucleotides
output	5 × [SimpleEntity:R-ALL-9836832] ribonucleotide [mitochondrial matrix]
precedingEvent	[Reaction:R-HSA-9836585] SUPV3L1:PNPT1 hydrolyzes mitochondrial RNA to yield 4-5 nucleotide oligoribonucleotides - Homo sapiens
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2023-09-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9841151] Anonymous, Reviewer, 2023-08-09
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9836822
summation	[Summation:9837244] The REXO2 dimer hydrolyzes the 4-5 nucleotide RNAs that are ...

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(hasEvent)

[Pathway:R-HSA-9836573] Mitochondrial RNA degradation

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