Reactome | SMAD2,3 and GATA6-AS1 lncRNA bind the GATA6 gene

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SMAD2,3 and GATA6-AS1 lncRNA bind the GATA6 gene Show undefined attributes

authored	[InstanceEdit:9823884] May, Bruce, 2023-01-11
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9823972] May, Bruce, 2023-01-13
dbId	9823959
displayName	SMAD2,3 and GATA6-AS1 lncRNA bind the GATA6 gene
edited	[InstanceEdit:9823884] May, Bruce, 2023-01-11
eventOf	[Pathway:R-HSA-9823730] Formation of definitive endoderm - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9823977] Expression of GATA6 in definitive endoderm - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-2888975] GATA6 gene [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9827615] GATA6-AS1 lncRNA [nucleoplasm] [DefinedSet:R-HSA-173511] p-2S-SMAD2,3:SMAD4 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2888922] Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors [LiteratureReference:9824465] GATA6-AS1 Regulates GATA6 Expression to Modulate Human Endoderm Differentiation
maxDepth	1
modified	[InstanceEdit:9830227] May, Bruce, 2023-02-28
name	SMAD2,3 and GATA6-AS1 lncRNA bind the GATA6 gene
output	[Complex:R-HSA-9823969] p-2S-SMAD2,3:GATA6-AS1 lncRNA:GATA6 gene [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-HSA-173488] The SMAD2/3:SMAD4 complex transfers to the nucleus - Homo sapiens
releaseDate	2023-03-29
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9830224] Salehin, Nazmus, 2023-02-28 [InstanceEdit:9830223] Tam, Patrick P L, 2023-02-28
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9823959
summation	[Summation:9825068] NODAL signaling in the anterior primitive streak causes phos...

Referrals

(hasEvent)	[Pathway:R-HSA-9823730] Formation of definitive endoderm
(precedingEvent)	[BlackBoxEvent:R-HSA-9823977] Expression of GATA6 in definitive endoderm

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