Reactome | Unknown efflux pump transports glucuronidated PRED metabolite

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9758872] Stephan, Ralf, 2021-11-26
category	uncertain
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9758869] Stephan, Ralf, 2021-11-26
dbId	9758868
displayName	Unknown efflux pump transports glucuronidated PRED metabolite
edited	[InstanceEdit:9767896] Stephan, Ralf, 2022-03-02
eventOf	[Pathway:R-HSA-9757110] Prednisone ADME - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:22548] xenobiotic transmembrane transport
input	[OtherEntity:R-ALL-9758665] glucuronidated PRED metabolite [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9758871] Efflux transport of estrogen glucuronides by human MRP2, MRP3, MRP4 and BCRP [LiteratureReference:9758870] Human efflux transport of testosterone, epitestosterone and other androgen glucuronides
maxDepth	1
modified	[InstanceEdit:9916945] Stephan, Ralf, 2024-07-29
name	Unknown efflux pump transports glucuronidated PRED metabolite
output	[OtherEntity:R-ALL-9758873] glucuronidated PRED metabolite [extracellular region]
precedingEvent	[Reaction:R-HSA-9758661] UGT2B7,2B17,1A3 glucuronidates PRED metabolites - Homo sapiens
releaseDate	2022-09-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9796130] Thorn, Caroline F, 2022-08-05
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9758868
summation	[Summation:9758874] Since glucuronide conjugates are hydrophilic, efflux transpo...

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