Since glucuronide conjugates are hydrophilic, efflux transpo...

created [InstanceEdit:9758869] Stephan, Ralf, 2021-11-26
dbId 9758874
displayName Since glucuronide conjugates are hydrophilic, efflux transpo...
modified [InstanceEdit:9770668] Stephan, Ralf, 2022-04-11
schemaClass Summation
text Since glucuronide conjugates are hydrophilic, efflux transporters mediate their excretion from tissues. It is not known which transporter is responsible for hepatic efflux of glucuronidated prednisone (PREDN) metabolites. The possible candidates are ABCC2 and ABCC3 which also export steroid hormone glucuronides from liver cells (Järvinen et al, 2018; Järvinen et al, 2019).
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