Reactome | ALB binds PREDN

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ALB binds PREDN Show undefined attributes

authored	[InstanceEdit:9757576] Stephan, Ralf, 2021-11-02
category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9757572] Stephan, Ralf, 2021-11-02
dbId	9757578
displayName	ALB binds PREDN
edited	[InstanceEdit:9767896] Stephan, Ralf, 2022-03-02
eventOf	[Pathway:R-HSA-9757110] Prednisone ADME - Homo sapiens
followingEvent	[Reaction:R-HSA-9762345] PREDN:ALB dissociates - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-194115] ALB [extracellular region] [ChemicalDrug:R-ALL-9660782] PREDN [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9757579] Plasma protein binding interaction of prednisone and prednisolone [LiteratureReference:9757575] The nonlinear pharmacokinetics of prednisone and prednisolone. II. Plasma protein binding of prednisone and prednisolone in rabbit and human plasma [LiteratureReference:9770659] Plasma free cortisol fraction reflects levels of functioning corticosteroid-binding globulin
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	ALB binds PREDN
negativePrecedingEvent	[NegativePrecedingEvent:9770653] Futile Cycle: PREDN:ALB dissociates
orthologousEvent	[Reaction:R-GGA-9757578] ALB binds PREDN - Gallus gallus [Reaction:R-XTR-9757578] ALB binds PREDN - Xenopus tropicalis [Reaction:R-SSC-9757578] ALB binds PREDN - Sus scrofa [Reaction:R-BTA-9757578] ALB binds PREDN - Bos taurus [Reaction:R-CFA-9757578] ALB binds PREDN - Canis familiaris [Reaction:R-RNO-9757578] ALB binds PREDN - Rattus norvegicus [Reaction:R-MMU-9757578] ALB binds PREDN - Mus musculus
output	[Complex:R-HSA-9757566] PREDN:ALB [extracellular region]
precedingEvent	[Reaction:R-HSA-9659680] ABCB1 transports xenobiotics out of the cell - Homo sapiens [Reaction:R-HSA-9762343] PREDL:ALB dissociates - Homo sapiens
releaseDate	2022-09-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9796130] Thorn, Caroline F, 2022-08-05
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9757578
summation	[Summation:9758959] Distribution and free concentration of various drugs can be ...

Referrals

(hasEvent)	[Pathway:R-HSA-9757110] Prednisone ADME
(precedingEvent)	[Reaction:R-HSA-9762345] PREDN:ALB dissociates