Reactome | IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane]

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IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] Show undefined attributes

catalystActivities	[CatalystActivity:975169] protein serine/threonine kinase activity of IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane]
compartment	[Compartment:74700] endosome membrane
consumedByEvent	[Reaction:R-HSA-975170] IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 - Homo sapiens
created	[InstanceEdit:975168] Shamovsky, V, 2010-09-22
dbId	975183
displayName	IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane]
hasComponent	4 × [EntityWithAccessionedSequence:R-HSA-975167] IRAK4 [endosome membrane] [Complex:R-HSA-975114] oligo-MyD88:activated TLR7-9 [endosome membrane]
inDisease	false
literatureReference	[LiteratureReference:937049] Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
maxDepth	7
modified	[InstanceEdit:9768151] Shamovsky, Veronica, 2022-03-04
name	IRAK4:oligo-MyD88:activated TLR 7/8 or 9
producedByEvent	[Reaction:R-HSA-975156] IRAK4 binds to the activated TLR7/8 or 9 receptor:MyD88 complex - Homo sapiens
relatedSpecies	[Species:9678119] Human SARS coronavirus [Species:164493] Human immunodeficiency virus 1 [Species:9031716] Influenza A virus [Species:9681683] Severe acute respiratory syndrome coronavirus 2
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-975183
updateTrackers	[UpdateTracker:9953885] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v93:[updateContainedComponent] [UpdateTracker:9873082] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v42:[addLiteratureReference, updateContainedComponent] [UpdateTracker:9903648] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v80:[updateContainedComponent] [UpdateTracker:9901536] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v74:[updateContainedComponent] [UpdateTracker:9871021] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9870264] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v38:[modifyName, updateContainedComponent] [UpdateTracker:9870027] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v36:[updateContainedComponent] [UpdateTracker:9902930] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v79:[updateContainedComponent] [UpdateTracker:9901321] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v73:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9953885] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v93:[updateContainedComponent] [UpdateTracker:9873082] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v42:[addLiteratureReference, updateContainedComponent] [UpdateTracker:9903648] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v80:[updateContainedComponent] [UpdateTracker:9901536] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v74:[updateContainedComponent] [UpdateTracker:9871021] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9870264] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v38:[modifyName, updateContainedComponent] [UpdateTracker:9870027] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v36:[updateContainedComponent] [UpdateTracker:9902930] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v79:[updateContainedComponent] [UpdateTracker:9901321] Update Tracker - [Complex:975183] IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v73:[updateContainedComponent]
(output)	[Reaction:R-HSA-975156] IRAK4 binds to the activated TLR7/8 or 9 receptor:MyD88 complex
(input)	[Reaction:R-HSA-975170] IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9
(physicalEntity)	[CatalystActivity:975169] protein serine/threonine kinase activity of IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane]

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