Reactome | IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane]

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IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] Show undefined attributes

compartment	[Compartment:74700] endosome membrane
created	[InstanceEdit:975168] Shamovsky, V, 2010-09-22
dbId	975113
displayName	IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane]
hasComponent	4 × [DefinedSet:R-HSA-975179] IRAK1/ IRAK2 [endosome membrane] [Complex:R-HSA-975159] p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 receptor [endosome membrane]
inDisease	false
literatureReference	[LiteratureReference:937049] Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling [LiteratureReference:975472] Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction
maxDepth	8
modified	[InstanceEdit:9768151] Shamovsky, Veronica, 2022-03-04
name	IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9
producedByEvent	[Reaction:R-HSA-975115] IRAK1/or IRAK2 binds to the activated IRAK4 :MyD88:activated TLR 7/8 or 9 - Homo sapiens
relatedSpecies	[Species:9678119] Human SARS coronavirus [Species:164493] Human immunodeficiency virus 1 [Species:9031716] Influenza A virus [Species:9681683] Severe acute respiratory syndrome coronavirus 2
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-975113
updateTrackers	[UpdateTracker:9901289] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v73:[updateContainedComponent] [UpdateTracker:9903146] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v80:[updateContainedComponent] [UpdateTracker:9901640] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v74:[updateContainedComponent] [UpdateTracker:9872947] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v42:[addLiteratureReference, updateContainedComponent] [UpdateTracker:9902830] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v79:[updateContainedComponent] [UpdateTracker:9871016] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v39:[updateContainedComponent] [UpdateTracker:9870448] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v38:[modifyName, updateContainedComponent] [UpdateTracker:9953869] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v93:[updateContainedComponent] [UpdateTracker:9869976] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v36:[updateContainedComponent]

Referrals

(updatedInstance)

[UpdateTracker:9901289] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v73:[updateContainedComponent]
[UpdateTracker:9903146] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v80:[updateContainedComponent]
[UpdateTracker:9901640] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v74:[updateContainedComponent]
[UpdateTracker:9872947] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v42:[addLiteratureReference, updateContainedComponent]
[UpdateTracker:9902830] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v79:[updateContainedComponent]
[UpdateTracker:9871016] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v39:[updateContainedComponent]
[UpdateTracker:9870448] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v38:[modifyName, updateContainedComponent]
[UpdateTracker:9953869] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v93:[updateContainedComponent]
[UpdateTracker:9869976] Update Tracker - [Complex:975113] IRAK1/or IRAK2 :p-S,2T-IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane] - v36:[updateContainedComponent]

(output)

[Reaction:R-HSA-975115] IRAK1/or IRAK2 binds to the activated IRAK4 :MyD88:activated TLR 7/8 or 9

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