Reactome | SARS-CoV-1 3a tetramer binds to CAV1

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SARS-CoV-1 3a tetramer binds to CAV1 Show undefined attributes

authored	[InstanceEdit:9731032] Stephan, Ralf, 2021-05-07
category	binding
compartment	[Compartment:190626] endoplasmic reticulum-Golgi intermediate compartment [Compartment:20699] Golgi membrane
created	[InstanceEdit:9731037] Stephan, Ralf, 2021-05-12
crossReference	[DatabaseIdentifier:12020764] Mondo:0005091
dbId	9731034
disease	[Disease:9678120] severe acute respiratory syndrome
displayName	SARS-CoV-1 3a tetramer binds to CAV1
edited	[InstanceEdit:9767957] Shamovsky, Veronica, 2022-03-02
eventOf	[Pathway:R-HSA-9735871] SARS-CoV-1 targets host intracellular signalling and regulatory pathways - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-204504] CAV1 [Golgi membrane] [Complex:R-COV-9685967] O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9731078] Severe acute respiratory syndrome coronavirus Orf3a protein interacts with caveolin
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SARS-CoV-1 3a tetramer binds to CAV1
orthologousEvent	[Reaction:R-HSA-9754518] SARS-CoV-2 3a tetramer binds to CAV1 - Homo sapiens
output	[Complex:R-HSA-9731025] CAV1:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment]
precedingEvent	[Reaction:R-HSA-9683746] Protein 3a forms a homotetramer - Homo sapiens
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2022-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9766195] Messina, Francesco, 2022-02-18
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9731034
summation	[Summation:9731071] SARS-CoV-1 viroporin 3a is a membrane protein that transloca...

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(hasEvent)

[Pathway:R-HSA-9735871] SARS-CoV-1 targets host intracellular signalling and regulatory pathways

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