Reactome | transit-amplifying cell of epidermis basal layer

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transit-amplifying cell of epidermis basal layer Show undefined attributes

cellType	[CellType:9725588] keratinocyte
consumedByEvent	[CellDevelopmentStep:R-HSA-9727354] Transit-amplifying cell of basal layer differentiates into keratinocyte of spinosum layer in interfollicular epidermis - Homo sapiens
created	[InstanceEdit:9725578] Orlic-Milacic, Marija, 2021-03-29
dbId	9725625
displayName	transit-amplifying cell of epidermis basal layer
inDisease	false
literatureReference	[LiteratureReference:9725617] Delayed onset of epidermal differentiation in psoriasis [LiteratureReference:9725598] Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study [LiteratureReference:9725607] K15 expression implies lateral differentiation within stratified epithelial basal cells [LiteratureReference:9725585] Keratinocyte Differentiation by Flow Cytometry [LiteratureReference:9725620] Localisation of keratin K78 in the basal layer and first suprabasal layers of stratified epithelia completes expression catalogue of type II keratins and provides new insights into sequential keratin expression
markerReference	[MarkerReference:9839321] Location and phenotype of human adult keratinocyte stem cells of the skin [MarkerReference:9725579] Delayed onset of epidermal differentiation in psoriasis [MarkerReference:9839322] Enrichment for murine keratinocyte stem cells based on cell surface phenotype [MarkerReference:9725550] K15 expression implies lateral differentiation within stratified epithelial basal cells [MarkerReference:9725597] KRT78 [cytosol] Localisation of keratin K78 in the basal layer and first suprabasal layers of stratified epithelia completes expression catalogue of type II keratins and provides new insights into sequential keratin expression [MarkerReference:9839486] Functional expression of AQP3 in human skin epidermis and reconstructed epidermis [MarkerReference:9725601] Epidermolysis bullosa simplex (Dowling-Meara type) is a genetic disease characterized by an abnormal keratin-filament network involving keratins K5 and K14
maxDepth	2
modified	[InstanceEdit:9839502] Orlic-Milacic, Marija, 2023-07-06
name	transit-amplifying cell of epidermis basal layer keratinocyte of basal layer of epidermis keratinocyte of skin epidermis stratum basale
organ	[Anatomy:9725577] skin of body
producedByEvent	[CellDevelopmentStep:R-HSA-9725621] Keratinocyte stem cell differentiates into transit amplifying cell in the basal layer of interfollicular epidermis - Homo sapiens
proteinMarker	[EntityWithAccessionedSequence:R-HSA-446074] KRT5 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-446091] KRT14 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-6809589] KRT15 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-6809631] KRT78 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-204439] ITGA6(24-1130) [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-917983] TFRC(1-760) [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-431723] AQP3 [plasma membrane] - Homo sapiens
schemaClass	Cell
species	[Species:48887] Homo sapiens
stId	R-HSA-9725625
tissue	[Anatomy:9725551] skin epidermis
tissueLayer	[Anatomy:9725619] stratum basale of epidermis

Referrals

(input)	[CellDevelopmentStep:R-HSA-9727354] Transit-amplifying cell of basal layer differentiates into keratinocyte of spinosum layer in interfollicular epidermis
(output)	[CellDevelopmentStep:R-HSA-9725621] Keratinocyte stem cell differentiates into transit amplifying cell in the basal layer of interfollicular epidermis
(cell)	[MarkerReference:9839321] Location and phenotype of human adult keratinocyte stem cells of the skin [MarkerReference:9725579] Delayed onset of epidermal differentiation in psoriasis [MarkerReference:9839322] Enrichment for murine keratinocyte stem cells based on cell surface phenotype [MarkerReference:9725550] K15 expression implies lateral differentiation within stratified epithelial basal cells [MarkerReference:9725597] KRT78 [cytosol] Localisation of keratin K78 in the basal layer and first suprabasal layers of stratified epithelia completes expression catalogue of type II keratins and provides new insights into sequential keratin expression [MarkerReference:9839486] Functional expression of AQP3 in human skin epidermis and reconstructed epidermis [MarkerReference:9725601] Epidermolysis bullosa simplex (Dowling-Meara type) is a genetic disease characterized by an abnormal keratin-filament network involving keratins K5 and K14

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