Reactome | GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG

Schema > Reaction > Entries

GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG Show undefined attributes

authored	[InstanceEdit:9717176] May, Bruce, 2021-03-05
catalystActivity	[CatalystActivity:9717204] phosphatidylinositol-4,5-bisphosphate phospholipase C activity of GNB1,3:GNG13:PLCB2:Ca2+ [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9717219] May, Bruce, 2021-03-08
crossReference	[DatabaseIdentifier:12667422] RHEA:33179
dbId	9717205
displayName	GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG
edited	[InstanceEdit:9717176] May, Bruce, 2021-03-05
eventOf	[Pathway:R-HSA-9717207] Sensory perception of sweet, bitter, and umami (glutamate) taste - Homo sapiens
followingEvent	[Reaction:R-HSA-9717214] I(1,4,5)P3 binds ITPR3 tetramer - Homo sapiens
inferredFrom	[Reaction:R-NUL-9717576] Gnb1:GNG2:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG - Bos taurus
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-179856] PI(4,5)P2 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG
output	[SimpleEntity:R-ALL-114519] DAG [plasma membrane] [SimpleEntity:R-ALL-114520] I(1,4,5)P3 [cytosol]
precedingEvent	[Reaction:R-HSA-9717193] GNB1,3:GNG13 binds PLCB2:Ca2+ - Homo sapiens
releaseDate	2021-09-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9749949] Jiang, Peihua, 2021-08-08
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9717205
summation	[Summation:9725119] The binding of the gustducin beta-gamma complex (GNB1,3:GNG1...

Referrals

(hasEvent)	[Pathway:R-HSA-9717207] Sensory perception of sweet, bitter, and umami (glutamate) taste
(precedingEvent)	[Reaction:R-HSA-9717214] I(1,4,5)P3 binds ITPR3 tetramer
(inferredTo)	[Reaction:R-NUL-9717576] Gnb1:GNG2:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG

Cite Us!