Reactome | GNB1,3:GNG13 binds PLCB2:Ca2+

Schema > Reaction > Entries

authored	[InstanceEdit:9717176] May, Bruce, 2021-03-05
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9717219] May, Bruce, 2021-03-08
dbId	9717193
displayName	GNB1,3:GNG13 binds PLCB2:Ca2+
edited	[InstanceEdit:9717176] May, Bruce, 2021-03-05
eventOf	[Pathway:R-HSA-9717207] Sensory perception of sweet, bitter, and umami (glutamate) taste - Homo sapiens
followingEvent	[Reaction:R-HSA-9717205] GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG - Homo sapiens
inferredFrom	[Reaction:R-NUL-9717194] Gnb1:GNG2 binds PLCB2 - Bos taurus
input	[Complex:R-HSA-9717185] GNB1,3:GNG13 [plasma membrane] [Complex:R-HSA-1604651] PLCB2:Ca2+ [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	GNB1,3:GNG13 binds PLCB2:Ca2+
output	[Complex:R-HSA-9717209] GNB1,3:GNG13:PLCB2:Ca2+ [plasma membrane]
precedingEvent	[Reaction:R-HSA-9717182] L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP and GNAT3:GTP, and GNB1,3:GNG13 - Homo sapiens
releaseDate	2021-09-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9749949] Jiang, Peihua, 2021-08-08
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9717193
summation	[Summation:9718309] The gustducin beta-gamma complex (GNB1,3:GNG13) dissociates ...

(hasEvent)	[Pathway:R-HSA-9717207] Sensory perception of sweet, bitter, and umami (glutamate) taste
(precedingEvent)	[Reaction:R-HSA-9717205] GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG
(inferredTo)	[Reaction:R-NUL-9717194] Gnb1:GNG2 binds PLCB2

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