Reactome | SQSTM1(2-251)-ALK(1058-1620) fusion [cytosol]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-HSA-9700080] ALK fusion proteins [cytosol] - Homo sapiens
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9712008] SQSTM1(2-251)-ALK(1058-1620) fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-9712008] SQSTM1(2-251)-ALK(1058-1620) fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:9711957] Rothfels, Karen, 2021-01-13
crossReference	[DatabaseIdentifier:12020833] Mondo:0005061 [DatabaseIdentifier:9711750] COSMIC:COSF1051
dbId	9711954
disease	[Disease:9632617] diffuse large B-cell lymphoma [Disease:8853117] lung adenocarcinoma
displayName	SQSTM1(2-251)-ALK(1058-1620) fusion [cytosol]
endCoordinate	251
hasModifiedResidue	[FragmentInsertionModification:9711919] Insertion of residues 1058 to 1620 at 252 from UniProt:Q9UM73 ALK
inDisease	true
literatureReference	[LiteratureReference:9711814] Identification of a novel fusion, SQSTM1-ALK, in ALK-positive large B-cell lymphoma [LiteratureReference:9711812] Novel ALK fusion partners in lung cancer
maxDepth	1
name	SQSTM1(2-251)-ALK(1058-1620) fusion Sequestosome-1 SQSTM_HUMAN
referenceEntity	[ReferenceGeneProduct:uniprot:Q13501] UniProt:Q13501 SQSTM1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9711954
startCoordinate	2

(hasCandidate)	[CandidateSet:R-HSA-9700080] ALK fusion proteins [cytosol]
(hasComponent)	[Complex:R-HSA-9712008] SQSTM1(2-251)-ALK(1058-1620) fusion dimer [cytosol]

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