Reactome | Spike protein forms a homotrimer

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Spike protein forms a homotrimer Show undefined attributes

authored	[InstanceEdit:9696918] Stephan, Ralf, 2020-07-22
category	binding
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:9694660] Cook, Justin, 2020-07-07
crossReference	[DatabaseIdentifier:12020746] Mondo:0100096
dbId	9694467
disease	[Disease:9683912] COVID-19
displayName	Spike protein forms a homotrimer
edited	[InstanceEdit:9698836] Stephan, Ralf, 2020-08-28
eventOf	[Pathway:R-HSA-9694548] Maturation of spike protein - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9694656] Spike trimer glycoside chains are extended - Homo sapiens
input	3 × [EntityWithAccessionedSequence:R-COV-9696943] high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9696817] Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Spike protein forms a homotrimer
output	[Complex:R-COV-9696901] high-mannose N-glycan-PALM-Spike trimer [endoplasmic reticulum-Golgi intermediate compartment]
precedingEvent	[Reaction:R-HSA-9694341] Spike protein gets palmitoylated - Homo sapiens
relatedSpecies	[Species:9681683] Severe acute respiratory syndrome coronavirus 2
releaseDate	2020-09-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9699044] Acencio, Marcio Luis, 2020-09-09
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9694467
summation	[Summation:9694616] The SARS-Cov spike protein forms a homotrimer, both in solut...
updateTrackers	[UpdateTracker:9775036] Update Tracker - [Reaction:9694467] Spike protein forms a homotrimer - v80:[add_removeInput, add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9775036] Update Tracker - [Reaction:9694467] Spike protein forms a homotrimer - v80:[add_removeInput, add_removeOutput]
(hasEvent)	[Pathway:R-HSA-9694548] Maturation of spike protein
(precedingEvent)	[BlackBoxEvent:R-HSA-9694656] Spike trimer glycoside chains are extended

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