Reactome | nsp9 forms a homotetramer

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nsp9 forms a homotetramer Show undefined attributes

authored	[InstanceEdit:9696945] Stephan, Ralf, 2020-07-30
category	uncertain
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9694660] Cook, Justin, 2020-07-07
crossReference	[DatabaseIdentifier:12020746] Mondo:0100096
dbId	9694261
disease	[Disease:9683912] COVID-19
displayName	nsp9 forms a homotetramer
edited	[InstanceEdit:9698832] Stephan, Ralf, 2020-08-28
eventOf	[Pathway:R-HSA-9694301] Maturation of replicase proteins - Homo sapiens
input	4 × [DefinedSet:R-COV-9694383] nsp9 [cytosol]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9697003] Crystal Structure of the SARS-CoV-2 Non-structural Protein 9, Nsp9 [LiteratureReference:9684279] Severe acute respiratory syndrome coronavirus nsp9 dimerization is essential for efficient viral growth [LiteratureReference:9762553] Structural basis for the multimerization of nonstructural protein nsp9 from SARS-CoV-2
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	nsp9 forms a homotetramer
output	[Complex:R-COV-9694286] nsp9 tetramer [cytosol]
precedingEvent	[Reaction:R-HSA-9694551] 3CLp cleaves nsp6-11 - Homo sapiens [Reaction:R-HSA-9694441] 3CLp cleaves pp1a - Homo sapiens [Reaction:R-HSA-9694732] 3CLp cleaves pp1ab - Homo sapiens
relatedSpecies	[Species:9681683] Severe acute respiratory syndrome coronavirus 2
releaseDate	2020-09-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9699044] Acencio, Marcio Luis, 2020-09-09
revised	[InstanceEdit:9735236] Stephan, Ralf, 2021-06-24
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9694261
summation	[Summation:9694596] Nonstructural protein 9 from SARS-Cov-2 is an obligate homod...

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(hasEvent)

[Pathway:R-HSA-9694301] Maturation of replicase proteins

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