Reactome | PDGFR mutant dimers [plasma membrane]

Schema > DefinedSet > Entries

catalystActivities	[CatalystActivity:9672169] protein tyrosine kinase activity of PDGFR mutant dimers [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-9672175] Autophosphorylation of PDGFR mutant dimers - Homo sapiens
created	[InstanceEdit:9672127] Rothfels, Karen, 2019-12-23
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9672131
disease	[Disease:1500689] cancer
displayName	PDGFR mutant dimers [plasma membrane]
hasMember	[CandidateSet:R-HSA-9672128] juxtamembrane domain PDGFRA mutant dimers [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9672126] kinase domain PDGFRA mutant dimers [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9672130] transmembrane domain PDGFRA mutant dimers [plasma membrane] - Homo sapiens
inDisease	true
maxDepth	4
name	PDGFR mutant dimers
producedByEvent	[Reaction:R-HSA-9672168] Ligand-independent dimerization of PDGFR mutants - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-9672131

(output)	[Reaction:R-HSA-9672168] Ligand-independent dimerization of PDGFR mutants
(input)	[Reaction:R-HSA-9672175] Autophosphorylation of PDGFR mutant dimers
(diseaseEntity)	[EntityFunctionalStatus:9672147] gain_of_function of PDGFR mutant dimers [plasma membrane]
(physicalEntity)	[CatalystActivity:9672169] protein tyrosine kinase activity of PDGFR mutant dimers [plasma membrane]

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