Reactome | kinase domain mutants of PDGFRA [plasma membrane]

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kinase domain mutants of PDGFRA [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9672127] Rothfels, Karen, 2019-12-23
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9672124
disease	[Disease:1500689] cancer
displayName	kinase domain mutants of PDGFRA [plasma membrane]
hasCandidate	[EntityWithAccessionedSequence:R-HSA-9674303] PDGFRA D842L [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9674306] PDGFRA D846V [plasma membrane] - Homo sapiens
hasMember	[EntityWithAccessionedSequence:R-HSA-9671549] PDGFRA D842V [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9671956] PDGFRA D842Y [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9671958] PDGFRA D846Y [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9671961] PDGFRA N848K [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9671974] PDGFRA Y849C [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9671547] PDGFRA D842_D846del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9671545] PDGFRA D842_H845del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9671563] PDGFRA D842_I843delinsV [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9671526] PDGFRA D842_M844del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9671538] PDGFRA D842del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9671559] PDGFRA D843_844del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9671552] PDGFRA D843_845del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9671537] PDGFRA I843_D846del [plasma membrane] - Homo sapiens
inDisease	true
literatureReference	[LiteratureReference:9671911] PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib
maxDepth	2
memberOf	[DefinedSet:R-HSA-9672123] PDGFR mutant receptors [plasma membrane] - Homo sapiens
modified	[InstanceEdit:9674384] Rothfels, Karen, 2020-01-13
name	kinase domain mutants of PDGFRA
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-9672124

Referrals

(hasMember)

[DefinedSet:R-HSA-9672123] PDGFR mutant receptors [plasma membrane]

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