Reactome | PDGFRA V561D [plasma membrane]

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PDGFRA V561D [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9672032] PDGFRA V561D dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9672032] PDGFRA V561D dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:9671534] Rothfels, Karen, 2019-12-19
crossReference	[DatabaseIdentifier:12020834] Mondo:0011719 [DatabaseIdentifier:9671543] COSMIC:COSV57265452 [DatabaseIdentifier:9671529] COSMIC:COSM12395
dbId	9671557
disease	[Disease:1500689] cancer [Disease:9661830] gastrointestinal stromal tumor
displayName	PDGFRA V561D [plasma membrane]
endCoordinate	1089
hasModifiedResidue	[ReplacedResidue:9671562] L-valine 561 replaced with L-aspartic acid
inDisease	true
maxDepth	1
memberOf	[CandidateSet:R-HSA-9672132] juxtamembrane domain mutants of PDGFRA [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-9672129] imatinib-sensitive PDGFR mutants [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-9673717] sorafenib-sensitive PDGFR mutants [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-9674344] avapritinib-sensitive PDGFR mutants [plasma membrane] - Homo sapiens
name	PDGFRA V561D Alpha platelet-derived growth factor receptor PGDS_HUMAN
referenceEntity	[ReferenceGeneProduct:uniprot:P16234] UniProt:P16234 PDGFRA
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9671557
startCoordinate	24

Referrals

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(hasComponent)

[Complex:R-HSA-9672032] PDGFRA V561D dimer [plasma membrane]

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