Reactome | KIT V560E [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

KIT V560E [plasma membrane] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-9669757] juxtamembrane domain KIT mutants [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9681384] ripretinib-sensitive KIT mutants [plasma membrane] - Homo sapiens
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9669699] KIT V560E dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9669699] KIT V560E dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:9669567] Rothfels, Karen, 2019-12-03
crossReference	[DatabaseIdentifier:12020834] Mondo:0011719 [DatabaseIdentifier:9669329] COSMIC:COSM22425 [DatabaseIdentifier:9669309] COSMIC:COSV55390849
dbId	9669566
disease	[Disease:9661830] gastrointestinal stromal tumor [Disease:1500689] cancer
displayName	KIT V560E [plasma membrane]
endCoordinate	976
hasModifiedResidue	[ReplacedResidue:9669530] L-valine 560 replaced with L-glutamic acid
inDisease	true
maxDepth	1
memberOf	[DefinedSet:R-HSA-9669841] sunitinib sensitive KIT mutants [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-9669825] regorafenib sensitive KIT mutants [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-9669834] sorafenib sensitive KIT mutants [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-9669768] nilotanib sensitive KIT mutants [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-9669766] masitinib sensitive KIT mutants [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-9669742] dovitinib sensitive KIT mutants [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-9669750] imatinib sensitive KIT mutants [plasma membrane] - Homo sapiens
name	KIT V560E Mast/stem cell growth factor receptor precursor KIT_HUMAN c-KIT
referenceEntity	[ReferenceGeneProduct:uniprot:P10721] UniProt:P10721 KIT
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9669566
startCoordinate	26

Referrals

(hasCandidate)	[CandidateSet:R-HSA-9669757] juxtamembrane domain KIT mutants [plasma membrane] [CandidateSet:R-HSA-9681384] ripretinib-sensitive KIT mutants [plasma membrane]
(hasComponent)	[Complex:R-HSA-9669699] KIT V560E dimer [plasma membrane]
(hasMember)	[DefinedSet:R-HSA-9669768] nilotanib sensitive KIT mutants [plasma membrane] [DefinedSet:R-HSA-9669834] sorafenib sensitive KIT mutants [plasma membrane] [DefinedSet:R-HSA-9669766] masitinib sensitive KIT mutants [plasma membrane] [DefinedSet:R-HSA-9669750] imatinib sensitive KIT mutants [plasma membrane] [DefinedSet:R-HSA-9669825] regorafenib sensitive KIT mutants [plasma membrane] [DefinedSet:R-HSA-9669841] sunitinib sensitive KIT mutants [plasma membrane] [DefinedSet:R-HSA-9669742] dovitinib sensitive KIT mutants [plasma membrane]