Reactome | juxtamembrane domain KIT mutants [plasma membrane]

Schema > CandidateSet > Entries

juxtamembrane domain KIT mutants [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-9669906] Ligand-independent dimerization of KIT juxtamembrane domain mutants - Homo sapiens [Reaction:R-HSA-9669906] Ligand-independent dimerization of KIT juxtamembrane domain mutants - Homo sapiens
created	[InstanceEdit:9669756] Rothfels, Karen, 2019-12-03
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9669757
disease	[Disease:1500689] cancer
displayName	juxtamembrane domain KIT mutants [plasma membrane]
hasCandidate	[EntityWithAccessionedSequence:R-HSA-9669547] KIT V559A [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669554] KIT V559G [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669557] KIT V559I [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669564] KIT V560D [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669566] KIT V560E [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669578] KIT W557G [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669581] KIT W557R [plasma membrane] - Homo sapiens
hasMember	[EntityWithAccessionedSequence:R-HSA-9669561] KIT V559_V560del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669444] KIT K550I;P551_V555del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669461] KIT K550_K558del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669433] KIT P551_V555del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669551] KIT V559D [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669569] KIT V560G [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9669446] KIT L576P [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9670336] KIT V560_L576del [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9670343] KIT W557_K558del [plasma membrane] - Homo sapiens
inDisease	true
maxDepth	2
modified	[InstanceEdit:9670358] Rothfels, Karen, 2019-12-09
name	juxtamembrane domain KIT mutants
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-9669757

Referrals

(input)	[Reaction:R-HSA-9669906] Ligand-independent dimerization of KIT juxtamembrane domain mutants
(diseaseEntity)	[EntityFunctionalStatus:9669905] gain_of_function of juxtamembrane domain KIT mutants [plasma membrane]

© 2026 Reactome

Cite Us!