PI3K bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR converts PIP2 to PIP3

authored
catalystActivity
category transition
compartment
created [InstanceEdit:9665414] Orlic-Milacic, Marija, 2019-10-30
crossReference
dbId 9665407
disease
displayName PI3K bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR converts PIP2 to PIP3
edited
entityFunctionalStatus
eventOf
input
isChimeric false
isInDisease true
isInferred false
literatureReference
modified [InstanceEdit:11879863] Wright, Adam, 2024-03-11
name
  • PI3K bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR converts PIP2 to PIP3
normalReaction [Reaction:R-HSA-1306957] PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR
output
precedingEvent
releaseDate 2020-03-17
reviewStatus [ReviewStatus:9821382] five stars
reviewed
schemaClass Reaction
species
stId R-HSA-9665407
summation
Cite Us!