Reactome | Antimicrobial action and antimicrobial resistance in Mtb

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Antimicrobial action and antimicrobial resistance in Mtb Show undefined attributes

authored	[InstanceEdit:9638888] Stephan, Ralf, 2019-03-06
created	[InstanceEdit:9639777] Jassal, Bijay, 2019-03-20
crossReference	[DatabaseIdentifier:12020769] Mondo:0018076
dbId	9639775
disease	[Disease:1660556] tuberculosis
displayName	Antimicrobial action and antimicrobial resistance in Mtb
edited	[InstanceEdit:9638883] Jassal, Bijay, 2019-03-06
eventOf	[Pathway:R-HSA-9635486] Infection with Mycobacterium tuberculosis - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:4701] response to antibiotic
hasDiagram	false
hasEHLD	false
hasEvent	[Polymerisation:R-HSA-9697085] RNAP transcribes Mtb RNA polyanion - Homo sapiens [Reaction:R-HSA-9697086] Rifampicin binds Mtb RNAP - Homo sapiens [Polymerisation:R-HSA-9697084] Defective RpoB in Mtb RNAP transcribes RNA polyanion - Homo sapiens
isInDisease	true
isInferred	false
lastUpdatedDate	2020-09-24
literatureReference	[LiteratureReference:9639634] Bacterial Protein Synthesis as a Target for Antibiotic Inhibition [LiteratureReference:9639632] Targeting the formation of the cell wall core of M. tuberculosis [LiteratureReference:9639633] The bacterial cell wall as a source of antibacterial targets [LiteratureReference:9638728] Evolution and ecology of antibiotic resistance genes [LiteratureReference:9638711] Antibiotic Resistance Mechanisms in Bacteria: Relationships Between Resistance Determinants of Antibiotic Producers, Environmental Bacteria, and Clinical Pathogens [LiteratureReference:9638705] Molecular mechanisms of antimicrobial tolerance and resistance in bacterial and fungal biofilms [LiteratureReference:9638742] The Role of Efflux and Physiological Adaptation in Biofilm Tolerance and Resistance
maxDepth	2
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	Antimicrobial action and antimicrobial resistance in Mtb
relatedSpecies	[Species:176806] Mycobacterium tuberculosis
releaseDate	2019-12-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9664478] Deffur, Armin, Wilkinson, RJ, 2019-10-23
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9639775
summation	[Summation:9640398] Antimicrobial compounds kill microorganisms or inhibit their...
updateTrackers	[UpdateTracker:9776816] Update Tracker - [Pathway:9639775] Antimicrobial action and antimicrobial resistance in Mtb - v74:[add_removeHasEvent]

Referrals

(updatedInstance)	[UpdateTracker:9776816] Update Tracker - [Pathway:9639775] Antimicrobial action and antimicrobial resistance in Mtb - v74:[add_removeHasEvent]
(hasEvent)	[Pathway:R-HSA-9635486] Infection with Mycobacterium tuberculosis

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