Reactome | PDE3A hydrolyses cAMP to AMP

Schema > Reaction > Entries

PDE3A hydrolyses cAMP to AMP Show undefined attributes

authored	[InstanceEdit:418565] Jupe, S, 2009-04-23 15:40:54 [InstanceEdit:9629668] Jassal, Bijay, 2018-11-23
catalystActivity	[CatalystActivity:9629666] 3',5'-cyclic-AMP phosphodiesterase activity of PDE3A [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9629668] Jassal, Bijay, 2018-11-23
crossReference	[DatabaseIdentifier:12667490] RHEA:25278
dbId	9629675
displayName	PDE3A hydrolyses cAMP to AMP
edited	[InstanceEdit:9629668] Jassal, Bijay, 2018-11-23
eventOf	[Pathway:R-HSA-418555] G alpha (s) signalling events - Homo sapiens
input	[SimpleEntity:R-ALL-30389] cAMP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:425627] Cyclic nucleotide phosphodiesterase-mediated integration of cGMP and cAMP signaling in cells of the cardiovascular system
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	PDE3A hydrolyses cAMP to AMP
orthologousEvent	[Reaction:R-BTA-9629675] PDE3A hydrolyses cAMP to AMP - Bos taurus [Reaction:R-PFA-9629675] PDE3A hydrolyses cAMP to AMP - Plasmodium falciparum [Reaction:R-SCE-9629675] PDE3A hydrolyses cAMP to AMP - Saccharomyces cerevisiae [Reaction:R-DDI-9629675] PDE3A hydrolyses cAMP to AMP - Dictyostelium discoideum [Reaction:R-CEL-9629675] PDE3A hydrolyses cAMP to AMP - Caenorhabditis elegans [Reaction:R-GGA-9629675] PDE3A hydrolyses cAMP to AMP - Gallus gallus [Reaction:R-SSC-9629675] PDE3A hydrolyses cAMP to AMP - Sus scrofa [Reaction:R-CFA-9629675] PDE3A hydrolyses cAMP to AMP - Canis familiaris [Reaction:R-RNO-9629675] PDE3A hydrolyses cAMP to AMP - Rattus norvegicus [Reaction:R-MMU-9629675] PDE3A hydrolyses cAMP to AMP - Mus musculus
output	[SimpleEntity:R-ALL-76577] AMP [cytosol]
precedingEvent	[Reaction:R-HSA-392129] Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate - Homo sapiens
releaseDate	2009-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:425201] Akkerman, JW, 2009-06-03 [InstanceEdit:9012014] Varusai, Thawfeek, 2017-07-10
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9629675
summation	[Summation:9629667] Cyclic nucleotide phosphodiesterases (PDEs) are a large fami...
updateTrackers	[UpdateTracker:9776610] Update Tracker - [Reaction:9629675] PDE3A hydrolyses cAMP to AMP - v75:[modifyText, removeRegulator]

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(updatedInstance)	[UpdateTracker:9776610] Update Tracker - [Reaction:9629675] PDE3A hydrolyses cAMP to AMP - v75:[modifyText, removeRegulator]
(hasEvent)	[Pathway:R-HSA-418555] G alpha (s) signalling events