PDE3A hydrolyses cAMP to AMP

Stable Identifier
R-HSA-9629675
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Cyclic nucleotide phosphodiesterases (PDEs) are a large family of enzymes that regulate signal transduction by the second messenger molecules cAMP and cGMP (Maurice 2005). PDEs are important as drug targets:PDE3A inhibition promotes cardiac muscle contraction, a strategy used in heart failure.

Literature References
Participants
Output
Participates
Catalyst Activity

3',5'-cyclic-AMP phosphodiesterase activity of PDE3A [cytosol]

Orthologous Events
Authored
Reviewed
Created
Cite Us!