CAMKK2 phosphorylates AMPK

Stable Identifier
R-HSA-9619478
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Activated CAMKK2 (CaMKK-beta) phosphorylates the alpha subunit of AMP-activated kinase (AMPK). The CAMKK2 target site is evolutionarily conserved in two AMPK-alpha isoforms and corresponds to threonine 183 (T183) in PRKAA1 (AMPK-alpha1) and threonine 172 (T172) in PRKAA2 (AMPK-alpha2).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
calmodulin-dependent protein kinase activity of p-CAMKK2:CALM1:4xCa2+ [cytosol]
Physical Entity
Activity
Inferred From
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Created