Reactome | CaMKK phosphorylates CAMK4

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CaMKK phosphorylates CAMK4 Show undefined attributes

authored	[InstanceEdit:9624342] Orlic-Milacic, Marija, 2018-10-10
catalystActivity	[CatalystActivity:9619154] calcium/calmodulin-dependent protein kinase activity of p-CaMKK:CALM1:4xCa2+ [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9619126] Orlic-Milacic, Marija, 2018-09-14
dbId	9619125
displayName	CaMKK phosphorylates CAMK4
edited	[InstanceEdit:9628239] Orlic-Milacic, Marija, 2018-11-07
eventOf	[Pathway:R-HSA-442729] CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde - Homo sapiens [Pathway:R-HSA-111932] CaMK IV-mediated phosphorylation of CREB - Homo sapiens
followingEvent	[Reaction:R-HSA-111915] CAMK4 autophosphorylates - Homo sapiens
inferredFrom	[Reaction:R-RNO-9619165] Camkk1 phosphorylates Camk4 - Rattus norvegicus [Reaction:R-NUL-9619177] Camkk2 phosphorylates CAMK4 - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-HSA-112281] CAMK4:CALM1:4xCa2+ [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CaMKK phosphorylates CAMK4
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [Complex:R-HSA-9619152] p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm]
precedingEvent	[Reaction:R-HSA-111913] Calmodulin binds CAMK4 - Homo sapiens [Reaction:R-HSA-442749] CaMKK autophosphorylates in the nucleus - Homo sapiens
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9627687] Yi, Feng, 2018-11-02 [InstanceEdit:9628437] Hansen, Kasper B, 2018-11-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9619125
summation	[Summation:9619160] Activated CaMKKs, CAMKK1 (CaMKK-alpha) and CAMKK2 (CaMKK-bet...

Referrals

(hasEvent)	[Pathway:R-HSA-442729] CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde [Pathway:R-HSA-111932] CaMK IV-mediated phosphorylation of CREB
(precedingEvent)	[Reaction:R-HSA-111915] CAMK4 autophosphorylates
(inferredTo)	[Reaction:R-RNO-9619165] Camkk1 phosphorylates Camk4 [Reaction:R-NUL-9619177] Camkk2 phosphorylates CAMK4

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