Reactome | CaMK IV-mediated phosphorylation of CREB

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CaMK IV-mediated phosphorylation of CREB Show undefined attributes

authored	[InstanceEdit:112007] Le Novere, N, Jassal, B, 2004-03-31 12:22:05
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:111899] Schmidt, EE, 2004-03-25 09:46:54
crossReference	[DatabaseIdentifier:12819497] BioModels Database:BIOMD0000000467 [DatabaseIdentifier:12819463] BioModels Database:BIOMD0000000088 [DatabaseIdentifier:12819511] BioModels Database:BIOMD0000000468
dbId	111932
displayName	CaMK IV-mediated phosphorylation of CREB
edited	[InstanceEdit:379927] Jassal, Bijay, 2008-11-06
eventOf	[Pathway:R-HSA-111933] Calmodulin induced events - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-442725] CaMKII binds activated calmodulin - Homo sapiens [Reaction:R-HSA-9617583] CaMKII autophosphorylates - Homo sapiens [Reaction:R-HSA-9619127] CAMK4 binds KPNA2 - Homo sapiens [BlackBoxEvent:R-HSA-112282] CAMK4 enters the nucleus - Homo sapiens [BlackBoxEvent:R-HSA-444792] Calmodulin-bound CaMKII-gamma enters the nucleus - Homo sapiens [Reaction:R-HSA-9618834] Activated calmodulin dissociates from CaMKII-gamma - Homo sapiens [Reaction:R-HSA-111913] Calmodulin binds CAMK4 - Homo sapiens [Reaction:R-HSA-9618863] CaMKK binds activated calmodulin in the nucleus - Homo sapiens [Reaction:R-HSA-442749] CaMKK autophosphorylates in the nucleus - Homo sapiens [Reaction:R-HSA-9619125] CaMKK phosphorylates CAMK4 - Homo sapiens [Reaction:R-HSA-111915] CAMK4 autophosphorylates - Homo sapiens [Reaction:R-HSA-111912] CaMK4 phosphorylates CREB1 - Homo sapiens [Reaction:R-HSA-111916] Dimerization of p-S133-CREB1 - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2023-03-29
literatureReference	[LiteratureReference:379824] The Ca-calmodulin-dependent protein kinase cascade
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	CaMK IV-mediated phosphorylation of CREB
orthologousEvent	[Pathway:R-RNO-111932] CaMK IV-mediated phosphorylation of CREB - Rattus norvegicus [Pathway:R-CEL-111932] CaMK IV-mediated phosphorylation of CREB - Caenorhabditis elegans [Pathway:R-DME-111932] CaMK IV-mediated phosphorylation of CREB - Drosophila melanogaster [Pathway:R-BTA-111932] CaMK IV-mediated phosphorylation of CREB - Bos taurus [Pathway:R-CFA-111932] CaMK IV-mediated phosphorylation of CREB - Canis familiaris [Pathway:R-MMU-111932] CaMK IV-mediated phosphorylation of CREB - Mus musculus
releaseDate	2008-12-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:379937] Castagnoli, L, 2008-11-06 12:55:54
revised	[InstanceEdit:9624342] Orlic-Milacic, Marija, 2018-10-10
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-111932
summation	[Summation:379820] The Ca2+-calmodulin-dependent protein kinase (CaM kinase) ca...
updateTrackers	[UpdateTracker:9790485] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v33:[addHasEvent] [UpdateTracker:9785272] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v52:[removeHasEvent] [UpdateTracker:9846680] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v84:[updateContainedRLE] [UpdateTracker:9791367] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v31:[removeHasEvent] [UpdateTracker:9781873] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v60:[addHasEvent] [UpdateTracker:9779078] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v66:[updateContainedRLE] [UpdateTracker:9864063] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v88:[updateContainedRLE] [UpdateTracker:9778749] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v67:[addHasEvent, updateContainedRLE]

Referrals

(updatedInstance)

[UpdateTracker:9790485] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v33:[addHasEvent]
[UpdateTracker:9785272] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v52:[removeHasEvent]
[UpdateTracker:9846680] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v84:[updateContainedRLE]
[UpdateTracker:9791367] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v31:[removeHasEvent]
[UpdateTracker:9781873] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v60:[addHasEvent]
[UpdateTracker:9779078] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v66:[updateContainedRLE]
[UpdateTracker:9864063] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v88:[updateContainedRLE]
[UpdateTracker:9778749] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v67:[addHasEvent, updateContainedRLE]

(hasEvent)

[Pathway:R-HSA-111933] Calmodulin induced events

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