Reactome | Unwinding DNA for the nascent transcript

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Unwinding DNA for the nascent transcript Show undefined attributes

authored	[InstanceEdit:75951] Timmers, H. T. M., 2003-09-11 07:42:30
catalystActivity	[CatalystActivity:109879] 3'-5' DNA helicase activity of TFIIH [nucleoplasm]
category	uncertain
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9613488] Gillespie, Marc E, 2018-07-13
dbId	9613497
displayName	Unwinding DNA for the nascent transcript
edited	[InstanceEdit:165073] Joshi-Tope, G, 0000-00-00 00:00:00
eventOf	[Pathway:R-HSA-73776] RNA Polymerase II Promoter Escape - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9613494] Unwinding of DNA for the Nascent Transcript: Second Transition - Homo sapiens
input	[SimpleEntity:R-ALL-9757634] NTP [nucleoplasm] [Complex:R-HSA-109878] pol II transcription complex [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation. [LiteratureReference:111262] Translocation after synthesis of a four-nucleotide RNA commits RNA polymerase II to promoter escape. [LiteratureReference:9613486] DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Unwinding DNA for the nascent transcript
orthologousEvent	[BlackBoxEvent:R-HSA-9613498] Unwinding of DNA for the nascent HIV-1 transcript - Homo sapiens [BlackBoxEvent:R-SCE-9613497] Unwinding DNA for the nascent transcript - Saccharomyces cerevisiae [BlackBoxEvent:R-SPO-9613497] Unwinding DNA for the nascent transcript - Schizosaccharomyces pombe [BlackBoxEvent:R-DDI-9613497] Unwinding DNA for the nascent transcript - Dictyostelium discoideum [BlackBoxEvent:R-CEL-9613497] Unwinding DNA for the nascent transcript - Caenorhabditis elegans [BlackBoxEvent:R-DME-9613497] Unwinding DNA for the nascent transcript - Drosophila melanogaster [BlackBoxEvent:R-GGA-9613497] Unwinding DNA for the nascent transcript - Gallus gallus [BlackBoxEvent:R-XTR-9613497] Unwinding DNA for the nascent transcript - Xenopus tropicalis [BlackBoxEvent:R-DRE-9613497] Unwinding DNA for the nascent transcript - Danio rerio [BlackBoxEvent:R-SSC-9613497] Unwinding DNA for the nascent transcript - Sus scrofa [BlackBoxEvent:R-BTA-9613497] Unwinding DNA for the nascent transcript - Bos taurus [BlackBoxEvent:R-CFA-9613497] Unwinding DNA for the nascent transcript - Canis familiaris [BlackBoxEvent:R-RNO-9613497] Unwinding DNA for the nascent transcript - Rattus norvegicus [BlackBoxEvent:R-MMU-9613497] Unwinding DNA for the nascent transcript - Mus musculus
output	[Complex:R-HSA-109878] pol II transcription complex [nucleoplasm] [SimpleEntity:R-ALL-113541] PPi [nucleoplasm]
precedingEvent	[Reaction:R-HSA-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9613497
summation	[Summation:9613489] The human BTF2 basic transcription factor (also called TFIIH...
updateTrackers	[UpdateTracker:9775428] Update Tracker - [BlackBoxEvent:9613497] Unwinding DNA for the nascent transcript - v79:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9775428] Update Tracker - [BlackBoxEvent:9613497] Unwinding DNA for the nascent transcript - v79:[add_removeInput]
(hasEvent)	[Pathway:R-HSA-73776] RNA Polymerase II Promoter Escape
(precedingEvent)	[BlackBoxEvent:R-HSA-9613494] Unwinding of DNA for the Nascent Transcript: Second Transition

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