Reactome | Newly Formed Phosphodiester Bond Stabilized and PPi Released

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Newly Formed Phosphodiester Bond Stabilized and PPi Released Show undefined attributes

category	dissociation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:75951] Timmers, H. T. M., 2003-09-11 07:42:30
dbId	75864
displayName	Newly Formed Phosphodiester Bond Stabilized and PPi Released
eventOf	[Pathway:R-HSA-75953] RNA Polymerase II Transcription Initiation - Homo sapiens
followingEvent	[Reaction:R-HSA-73946] Abortive initiation after formation of the first phosphodiester bond - Homo sapiens [BlackBoxEvent:R-HSA-75850] Addition of the third nucleotide on the nascent transcript - Homo sapiens [BlackBoxEvent:R-HSA-9613497] Unwinding DNA for the nascent transcript - Homo sapiens
input	[Complex:R-HSA-83601] Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation.
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	Newly Formed Phosphodiester Bond Stabilized and PPi Released
orthologousEvent	[Reaction:R-HSA-167134] Newly formed phosphodiester bond stabilized and PPi released - Homo sapiens [Reaction:R-SCE-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Saccharomyces cerevisiae [Reaction:R-SPO-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Schizosaccharomyces pombe [Reaction:R-DDI-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Dictyostelium discoideum [Reaction:R-CEL-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Caenorhabditis elegans [Reaction:R-DME-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Drosophila melanogaster [Reaction:R-GGA-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Gallus gallus [Reaction:R-XTR-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Xenopus tropicalis [Reaction:R-SSC-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Sus scrofa [Reaction:R-BTA-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Bos taurus [Reaction:R-CFA-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Canis familiaris [Reaction:R-RNO-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Rattus norvegicus [Reaction:R-MMU-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Mus musculus
output	[Complex:R-HSA-109878] pol II transcription complex [nucleoplasm] [SimpleEntity:R-ALL-113541] PPi [nucleoplasm]
precedingEvent	[Reaction:R-HSA-75866] Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-75864
summation	[Summation:178968] At the beginning of this reaction, 1 molecule of 'Pol II Ini...

Referrals

(hasEvent)	[Pathway:R-HSA-75953] RNA Polymerase II Transcription Initiation
(precedingEvent)	[Reaction:R-HSA-73946] Abortive initiation after formation of the first phosphodiester bond [BlackBoxEvent:R-HSA-75850] Addition of the third nucleotide on the nascent transcript [BlackBoxEvent:R-HSA-9613497] Unwinding DNA for the nascent transcript

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