Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
Pathway
>
Entries
RNA Polymerase II Promoter Escape
Show undefined attributes
Go to Details
authored
[InstanceEdit:75951] Timmers, H. T. M., 2003-09-11 07:42:30
compartment
[Compartment:7660] nucleoplasm
created
[InstanceEdit:75951] Timmers, H. T. M., 2003-09-11 07:42:30
dbId
73776
displayName
RNA Polymerase II Promoter Escape
edited
[InstanceEdit:165073] Joshi-Tope, G, 0000-00-00 00:00:00
eventOf
[Pathway:R-HSA-76042] RNA Polymerase II Transcription Initiation And Promoter Clearance - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:17842] transcription elongation by RNA polymerase II
hasDiagram
false
hasEHLD
false
hasEvent
[BlackBoxEvent:R-HSA-9613497] Unwinding DNA for the nascent transcript - Homo sapiens
[BlackBoxEvent:R-HSA-75850] Addition of the third nucleotide on the nascent transcript - Homo sapiens
[BlackBoxEvent:R-HSA-9613494] Unwinding of DNA for the Nascent Transcript: Second Transition - Homo sapiens
[BlackBoxEvent:R-HSA-75869] Addition of the fourth nucleotide on the Nascent Transcript: Second Transition - Homo sapiens
[Reaction:R-HSA-75873] Addition of Nucleotides 5 through 9 on the growing Transcript - Homo sapiens
[Reaction:R-HSA-76576] Addition of nucleotides 10 and 11 on the growing transcript: Third Transition - Homo sapiens
[Reaction:R-HSA-111264] Addition of nucleotides between position +11 and +30 - Homo sapiens
isInDisease
false
isInferred
false
lastUpdatedDate
2021-12-08
literatureReference
[LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation.
maxDepth
2
modified
[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name
RNA Polymerase II Promoter Escape
orthologousEvent
[Pathway:R-HSA-167162] RNA Polymerase II HIV Promoter Escape - Homo sapiens
[Pathway:R-PFA-73776] RNA Polymerase II Promoter Escape - Plasmodium falciparum
[Pathway:R-SCE-73776] RNA Polymerase II Promoter Escape - Saccharomyces cerevisiae
[Pathway:R-SPO-73776] RNA Polymerase II Promoter Escape - Schizosaccharomyces pombe
[Pathway:R-DDI-73776] RNA Polymerase II Promoter Escape - Dictyostelium discoideum
[Pathway:R-CEL-73776] RNA Polymerase II Promoter Escape - Caenorhabditis elegans
[Pathway:R-DME-73776] RNA Polymerase II Promoter Escape - Drosophila melanogaster
[Pathway:R-GGA-73776] RNA Polymerase II Promoter Escape - Gallus gallus
[Pathway:R-XTR-73776] RNA Polymerase II Promoter Escape - Xenopus tropicalis
[Pathway:R-DRE-73776] RNA Polymerase II Promoter Escape - Danio rerio
[Pathway:R-SSC-73776] RNA Polymerase II Promoter Escape - Sus scrofa
[Pathway:R-BTA-73776] RNA Polymerase II Promoter Escape - Bos taurus
[Pathway:R-CFA-73776] RNA Polymerase II Promoter Escape - Canis familiaris
[Pathway:R-RNO-73776] RNA Polymerase II Promoter Escape - Rattus norvegicus
[Pathway:R-MMU-73776] RNA Polymerase II Promoter Escape - Mus musculus
releaseDate
2004-07-06
reviewStatus
[ReviewStatus:9821382] five stars
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-73776
summation
[Summation:75954] RNA Polymerase II promoter escape occurs after the first pho...
updateTrackers
[UpdateTracker:9782137] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v59:[updateContainedRLE]
[UpdateTracker:9789593] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v37:[updateContainedRLE]
[UpdateTracker:9783329] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v57:[updateContainedRLE]
[UpdateTracker:9784486] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v54:[updateContainedRLE]
[UpdateTracker:9784588] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v53:[updateContainedRLE]
[UpdateTracker:9779149] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v66:[addHasEvent, updateContainedRLE]
[UpdateTracker:9775389] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v79:[updateContainedRLE]
Referrals
(updatedInstance)
[UpdateTracker:9782137] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v59:[updateContainedRLE]
[UpdateTracker:9789593] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v37:[updateContainedRLE]
[UpdateTracker:9783329] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v57:[updateContainedRLE]
[UpdateTracker:9784486] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v54:[updateContainedRLE]
[UpdateTracker:9784588] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v53:[updateContainedRLE]
[UpdateTracker:9779149] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v66:[addHasEvent, updateContainedRLE]
[UpdateTracker:9775389] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v79:[updateContainedRLE]
(hasEvent)
[Pathway:R-HSA-76042] RNA Polymerase II Transcription Initiation And Promoter Clearance
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text