Reactome | ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG

Schema > Reaction > Entries

ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG Show undefined attributes

authored	[InstanceEdit:9605616] Jassal, Bijay, 2018-04-16
catalystActivity	[CatalystActivity:9605669] beta-galactoside (CMP) alpha-2,3-sialyltransferase activity of ST3GAL3,4,6 [Golgi membrane]
category	transition
compartment	[Compartment:17963] Golgi lumen [Compartment:20699] Golgi membrane
created	[InstanceEdit:9605616] Jassal, Bijay, 2018-04-16
dbId	9605600
displayName	ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG
edited	[InstanceEdit:9605616] Jassal, Bijay, 2018-04-16
eventOf	[Pathway:R-HSA-9037629] Lewis blood group biosynthesis - Homo sapiens
followingEvent	[Reaction:R-HSA-9605700] B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda - Homo sapiens [Reaction:R-HSA-9605682] FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX - Homo sapiens
input	[SimpleEntity:R-ALL-727815] CMP-Neu5Ac [Golgi lumen] [SimpleEntity:R-ALL-9033790] Type 2 chain [Golgi lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1025951] Cloning of a novel alpha 2,3-sialyltransferase that sialylates glycoprotein and glycolipid carbohydrate groups [LiteratureReference:2046268] Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids [LiteratureReference:981485] Cloning and expression of human Gal beta 1,3(4)GlcNAc alpha 2,3-sialyltransferase
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG
orthologousEvent	[Reaction:R-BTA-9605600] ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG - Bos taurus [Reaction:R-GGA-9605600] ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG - Gallus gallus [Reaction:R-XTR-9605600] ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG - Xenopus tropicalis [Reaction:R-DRE-9605600] ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG - Danio rerio [Reaction:R-SSC-9605600] ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG - Sus scrofa [Reaction:R-CFA-9605600] ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG - Canis familiaris [Reaction:R-RNO-9605600] ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG - Rattus norvegicus [Reaction:R-MMU-9605600] ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG - Mus musculus
output	[SimpleEntity:R-ALL-727810] CMP [Golgi lumen] [SimpleEntity:R-ALL-9605685] Type 2 MSGG [Golgi lumen]
releaseDate	2019-03-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9632249] Matsui, Taei, 2018-12-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9605600
summation	[Summation:9605645] The alpha-2,3-sialyltransferases ST3GAL3,4 and 6 (Kitagawa &...

Referrals

(hasEvent)	[Pathway:R-HSA-9037629] Lewis blood group biosynthesis
(precedingEvent)	[Reaction:R-HSA-9605700] B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda [Reaction:R-HSA-9605682] FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX