Reactome | ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG

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ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG Show undefined attributes

catalystActivity	[CatalystActivity:10431934] beta-galactoside (CMP) alpha-2,3-sialyltransferase activity of ST3GAL3,4,6 [Golgi membrane]
category	transition
compartment	[Compartment:17963] Golgi lumen [Compartment:20699] Golgi membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10431936
displayName	ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG
eventOf	[Pathway:R-BTA-9037629] Lewis blood group biosynthesis - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-9605700] B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda - Bos taurus [Reaction:R-BTA-9605682] FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX - Bos taurus
inferredFrom	[Reaction:R-HSA-9605600] ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG - Homo sapiens
input	[SimpleEntity:R-ALL-727815] CMP-Neu5Ac [Golgi lumen] [SimpleEntity:R-ALL-9033790] Type 2 chain [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG
output	[SimpleEntity:R-ALL-727810] CMP [Golgi lumen] [SimpleEntity:R-ALL-9605685] Type 2 MSGG [Golgi lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9605600
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-BTA-9605700] B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda [Reaction:R-BTA-9605682] FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX
(hasEvent)	[Pathway:R-BTA-9037629] Lewis blood group biosynthesis
(inferredTo)	[Reaction:R-HSA-9605600] ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG

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