Reactome | activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10370616] protein serine/threonine kinase activity of activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane]
compartment	[Compartment:74700] endosome membrane
consumedByEvent	[Reaction:R-BTA-936951] Activation of TAK1 complex bound to activated TLR4 complex - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10370611
displayName	activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane]
hasComponent	[Complex:R-BTA-936965] K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] 2 × [Polymer:R-BTA-450152] K63polyUb [cytosol] 2 × [Complex:R-BTA-446878] TAK1 complex [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] - Homo sapiens
maxDepth	7
name	activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex
producedByEvent	[Reaction:R-BTA-936947] Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-936954
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-BTA-936951] Activation of TAK1 complex bound to activated TLR4 complex
(physicalEntity)	[CatalystActivity:10370616] protein serine/threonine kinase activity of activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane]
(output)	[Reaction:R-BTA-936947] Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex
(inferredTo)	[Complex:R-HSA-936954] activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane]

Cite Us!