Reactome | High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane]

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High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-914086] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-909738] SHP1 and SHP2 bind the common beta chain - Homo sapiens [Reaction:R-HSA-879934] Recruitment of SHC1 is mediated by Y593 of the common beta chain - Homo sapiens
created	[InstanceEdit:913398] Jupe, S, 2010-07-14
dbId	913422
displayName	High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane]
hasMember	[Complex:R-HSA-912317] IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] - Homo sapiens [Complex:R-HSA-913384] High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] - Homo sapiens [Complex:R-HSA-913359] High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] - Homo sapiens
inDisease	false
inferredTo	[DefinedSet:R-MMU-913422] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] - Mus musculus [DefinedSet:R-RNO-913422] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] - Rattus norvegicus [DefinedSet:R-CFA-913422] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] - Canis familiaris [DefinedSet:R-BTA-913422] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] - Bos taurus [DefinedSet:R-SSC-913422] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] - Sus scrofa [DefinedSet:R-GGA-913422] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] - Gallus gallus
maxDepth	6
modified	[InstanceEdit:914066] Jupe, S, 2010-07-21
name	High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc
producedByEvent	[Reaction:R-HSA-879907] Tyrosine kinases phosphorylate the receptor - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-913422
updateTrackers	[UpdateTracker:9870464] Update Tracker - [DefinedSet:913422] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] - v38:[updateContainedMemberOrCandidate]

Referrals

(updatedInstance)	[UpdateTracker:9870464] Update Tracker - [DefinedSet:913422] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] - v38:[updateContainedMemberOrCandidate]
(hasComponent)	[Complex:R-HSA-914086] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane]
(input)	[Reaction:R-HSA-909738] SHP1 and SHP2 bind the common beta chain [Reaction:R-HSA-879934] Recruitment of SHC1 is mediated by Y593 of the common beta chain
(output)	[Reaction:R-HSA-879907] Tyrosine kinases phosphorylate the receptor

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