Reactome | High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-BTA-914086] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] - Bos taurus
consumedByEvent	[Reaction:R-BTA-909738] SHP1 and SHP2 bind the common beta chain - Bos taurus [Reaction:R-BTA-879934] Recruitment of SHC1 is mediated by Y593 of the common beta chain - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10368974
displayName	High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane]
hasMember	[Complex:R-BTA-912317] IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] - Bos taurus [Complex:R-BTA-913384] High affinity GM-CSF receptor complex dimer, inactive JAK2, p(Y593, 628)- Bc [plasma membrane] - Bos taurus [Complex:R-BTA-913359] High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] - Bos taurus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-913422] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] - Homo sapiens
maxDepth	6
name	High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc
producedByEvent	[Reaction:R-BTA-879907] Tyrosine kinases phosphorylate the receptor - Bos taurus
schemaClass	DefinedSet
species	[Species:48898] Bos taurus
stId	R-BTA-913422

(input)	[Reaction:R-BTA-909738] SHP1 and SHP2 bind the common beta chain [Reaction:R-BTA-879934] Recruitment of SHC1 is mediated by Y593 of the common beta chain
(hasComponent)	[Complex:R-BTA-914086] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane]
(output)	[Reaction:R-BTA-879907] Tyrosine kinases phosphorylate the receptor
(inferredTo)	[DefinedSet:R-HSA-913422] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane]

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