Incorrectly folded glycoproteins translocate to the ERQC

Stable Identifier
R-HSA-912291
Type
Reaction [transition]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen, endoplasmic reticulum quality control compartment
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Incorrectly folded glycoproteins translocate to the ERQC
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Proteins with folding defects get transported to the Endoplasmic Reticulum Quality Control Compartment (Molinari, 2007).

Literature References
PubMed ID Title Journal Year
17510649 N-glycan structure dictates extension of protein folding or onset of disposal

Molinari, M

Nat Chem Biol 2007
Participants
Input
Output
Participant Of
hasEvent
Authored
Dall'Olio, GM  (2009-11-10)
Reviewed
Gagneux, P  (2010-08-17)
Created
Jassal, B  (2010-07-08)