Reactome | Release of p-STAT2:p-STAT1 dimer

Schema > Reaction > Entries

Release of p-STAT2:p-STAT1 dimer Show undefined attributes

authored	[InstanceEdit:909728] Garapati, P V, 2010-07-07
category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:909728] Garapati, P V, 2010-07-07
dbId	909722
displayName	Release of p-STAT2:p-STAT1 dimer
edited	[InstanceEdit:909728] Garapati, P V, 2010-07-07
eventOf	[Pathway:R-HSA-909733] Interferon alpha/beta signaling - Homo sapiens
followingEvent	[Reaction:R-HSA-909725] Interaction of IRF9 with p-STAT2:p-STAT1 - Homo sapiens
input	[Complex:R-HSA-909711] IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:909588] Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-alpha [LiteratureReference:909616] STAT activation and differential complex formation dictate selectivity of interferon responses
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Release of p-STAT2:p-STAT1 dimer
orthologousEvent	[Reaction:R-GGA-909722] Release of p-STAT2:p-STAT1 dimer - Gallus gallus [Reaction:R-DRE-909722] Release of p-STAT2:p-STAT1 dimer - Danio rerio [Reaction:R-SSC-909722] Release of p-STAT2:p-STAT1 dimer - Sus scrofa [Reaction:R-BTA-909722] Release of p-STAT2:p-STAT1 dimer - Bos taurus [Reaction:R-CFA-909722] Release of p-STAT2:p-STAT1 dimer - Canis familiaris [Reaction:R-RNO-909722] Release of p-STAT2:p-STAT1 dimer - Rattus norvegicus [Reaction:R-MMU-909722] Release of p-STAT2:p-STAT1 dimer - Mus musculus
output	[Complex:R-HSA-909704] IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] [Complex:R-HSA-909702] p-STAT2:p-STAT1 [cytosol]
precedingEvent	[Reaction:R-HSA-909726] Phosphorylation of STAT1 - Homo sapiens
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:933762] Abdul-Sater, AA, Schindler, C, 2010-08-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-909722
summation	[Summation:909660] The phosphorylated STAT2:STAT1 heterodimers thus formed disa...

Referrals

(hasEvent)	[Pathway:R-HSA-909733] Interferon alpha/beta signaling
(precedingEvent)	[Reaction:R-HSA-909725] Interaction of IRF9 with p-STAT2:p-STAT1