Release of p-STAT2:p-STAT1 dimer

Stable Identifier
R-HSA-909722
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
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The phosphorylated STAT2:STAT1 heterodimers thus formed disassociate from the IFNAR1 subunit and translocates to the nucleus.

Literature References
PubMed ID Title Journal Year
8621447 Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-alpha

Li, X, Leung, S, Qureshi, S, Darnell JE, Jr, Stark, GR

J Biol Chem 1996
17351669 STAT activation and differential complex formation dictate selectivity of interferon responses

Wesoly, J, Szweykowska-Kulinska, Z, Bluyssen, HA

Acta Biochim Pol 2007
Participants
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Orthologous Events
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